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- De Vries,
L., Zheng, B., Fischer, T., Elenko, E.,
and M. G. Farquhar 2000.
The Regulator of G Protein Signaling (RGS) family.
Annu. Rev. Pharmacol. & Toxicol. 40:235-271.
- Lin, P., Fischer, T., Weiss, T. and M. G. Farquhar.
2000. Calnuc, an
EF-hand Ca2+ binding protein, specifically interacts
with the C-terminal a5-Helix of Gai3. Proc. Natl. Acad. 97:674-679.
- Fischer, T., Elenko, E., Wan, L., Thomas, G. and M. G. Farquhar.
2000. Membrane associated GAIP is a phosphoprotein and can be phosphorylated
by clathrin-coated vesicles. Proc. Natl. Acad. Sci. 97:4040-4045.
- Zheng, B., Chen, D. and M.G. Farquhar 2000. MIR16, a putative
membrane glycerophosphodiester phosphodiesterase, interacts with
RGS16. Proc. Natl. Acad. Sci. 97:3999-4004.
- Takeda, T., Go, W., Orlando, R. A. and M. G. Farquhar. 2000.
Expression of podocalyxin inhibits cell-cell adhesion and modifies
junctional properties in Madin-Darby canine kidney cells. Mol. Biol.
Cell 11:3219-3232.
- Rader, K., Orlando, R. A., Lou, X., and M. G. Farquhar. 2000.
Identification and localization of ANKRA, a novel ankyrin repeat
protein that interacts with they cytoplasmic domain of megalin.
J. Amer. Soc. Nephrol. 11:2167-78.
- De Vries L., Fischer T., Tronchere H, Brothers G. M., Strockbine
B., Siderovski D. P., and M. G. Farquhar. 2000. Activator of G protein
signaling 3 is a guanine dissociation inhibitor for Gαi
subunits. Proc. Natl. Acad. Sci. 97:14364-14369.
- Rader, K., Boyer, A. D., Farquhar, M. G., and K. C. Arden,
2000. Assignment of ankyrin repeat, family A (RFXANK-like) 2 (ANKRA2)
to human chromosome 5q12-q13 by radiation hybrid mapping and somatic
cell hybrid PCR. Cytogenet. Cell Genet. 89:164-165.
- Sarti M, Farquhar MG, and R.A. Orlando, 2000. The receptor-associated
protein (RAP) interacts with several resident proteins of the endoplasmic
reticulum including a glycoprotein related to actin. Exp. Cell Res.
260:199-207.
- Lou, X. , Yano, H., Chao, M. V. and M. G. Farquhar. 2001.
GIPC and GAIP form a complex with TrkA: A putative link between
G-protein and receptor tyrosine kinase pathways. Mol. Biol. Cell
12:615-627.
- Czekay, R.-P., Kuemmel, T. A., Orlando, R. A., and M. G. Farquhar.
2001. Direct binding of occupied urokinase receptor (uPAR) to LDL
receptor-related protein (LRP) is required for endocytosis of uPAR
and regulation of cell surface urokinase (uPA) activity. Mol. Biol.
Cell 12:1467-1479.
- Orlando, R. A., T. Takeda, B. Zak, S. Schmieder, V. Benoit,
T. McQuistan, H. Furthmayr and M. G. Farquhar. 2001. The glomerular
epithelial cell anti-adhesin, podocalyxin, associates with the actin
cytoskeleton through interactions with ezrin. J. Amer. Soc. Nephrol.
12:1589-1598.
- Takeda, T., McQuistan, T., Orlando, R. A., and M. G. Farquhar.
2001. Loss of the glomerular foot process organization is associated
with uncoupling of podocalyxin from the actin cytoskeleton. J. Clinical
Invest. 108:289-301.
- Kimple, R. J., De Vries, L., Tronchere, H., Behe, C. I.,
Morris, R. A., Farquhar, M. G. and D. P. Siderovski. 2001.
RGS12 and RGS14 GoLoco motifs are Gαi
interaction sites with guanine nucleotide dissociation inhibitor
activity. J. Biol. Chem. 31:29275-29281.
- De Vries, L. and M. G. Farquhar. 2001. Screening for interacting
partners for Gai3 and RGS-GAIP using two-hybrid system. In: Methods
in Enzymology. R. Iyengar and J. D. Hildebrandt, eds. California:
Academic Press 344:657-673.
- 258 Zheng, B., Ma, Y-C, Ostrom, R.S., Lavoie, C., Gill, G., Insel,
P.A., Huang, X-Y, and M. G. Farquhar. 2001. RGS-PX1, GAP for Gαs
and a sorting nexin in vesicular trafficking. Science 294:1939-1942.
- Weiss, T. S., Chamberlain, C. E., Takeda, T., Lin, P., Hahn,
K. M., and M. G. Farquhar. 2001. Gai3 binding to calnuc on Golgi
membranes in living cells monitored by fluorescence resonance energy
transfer of green fluorescent protein fusion proteins. Proc. Natl.
Acad. Sci. 98:14961-14966.
- Schmieder, S., Takeda, T., and M. G. Farquhar. 2001. Increased
phosphorylation of podocalyxin in glomeruli
from PAN nephrotic and protamine sulfate treated rats. J.
Amer. Soc. Nephrol. 12:A3603.
- Lou, X., McQuistan, T., Orlando, R.A. and M. G. Farquhar.
2002. GAIP, GIPC and Gai3 are concentrated
in endocytic compartments of proximal tubule cells: putative role
in regulating megalin’s
function. J. Amer. Soc. Nephrol. 13:918-927.
- Lavoie, C., Meerloo, T., Lin, P. and M. G. Farquhar. 2002.
Calnuc, an EF-hand Ca2+-binding protein, is stored
and processed in the Golgi and secreted by the constitutive-like
pathway in AtT20 cells. Mol. Endocrin. 16:2462-2474.
- Takeda, T, Yamazaki H, and MG Farquhar, 2002. Identification
of apical sorting determinant in the cytoplasmic tail of
megalin. Am. J. Physiol. Cell Physol. 10.1152/ajpcell.00514.
- Zheng, B., Berrie, C.P., Corda, D., and Farquhar, M.G. 2003.
GDE1/MIR16 is a glycerophosphoinositol phosphodiesterase
regulated by stimulation of G protein-coupled receptors.
Proc. Natl. Acad. Sci. USA 100:1745-1750.
- 265. Chih-Min, T., Zheng, B., O’Connor, D. T., Wiley,
J. S., Farquhar, M. G. and P. A. Insel. 2003.
Identification of single nucleotide polymorphisms
(SNPs) in RGS-PX, novel proteins that function as negative regulators
for heterotrimeric GTP-binding proteins (G
proteins). FASEB J. 17:A218273.
- Derrien, A., Zheng, B., Osterhout, J. L., Ma, Y. C., Milligan,
G., Farquhar, M. G., and K. M. Druey. 2003.
Src-mediated RGS16 tyrosine phosphorylation promotes RGS16 stability.
J Biol Chem. 278:16107-16116.
- Elenko, E., Fischer, T., Niesman, I., McQuistan, T., Von
Zastrow, M. and M. G. Farquhar. 2003. Spatial Regulation of G protein
signaling in clathrin-coated membrane microdomains. Mol.
Pharmacol. 64:1-10.
- Fischer, T., De Vries, L., Meerloo, T. and M. G. Farquhar.
2003. Promotion of Gai3 subunit downregulation by GIPN,
a putative E3 ubiquitin ligase that interacts with RGS-GAIP.
Proc. Natl. Acad. Sci. 100:8270-8275.
- Nagai, M., Meerloo, T., Takeda, T., and M. G. Farquhar. 2003.
The adaptor protein ARH escorts megalin to and through endosomes.
Mol. Biol. Cell. 14:4984-4986.
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