• 1980 - 1984
  • 1985 - 1989
  • 1990 - 1994
  • 1995 - 1999
  • 2000 - 2004
  • 2005 - 2009
  • 2010 - 2014
  • 2015
  1. Goldstein LS, Hardy RW, Lindsley DL. Structural genes on the Y chromosome of Drosophila melanogaster.
    Proc Natl Acad Sci U S A. 1982 Dec;79(23):7405-9.
  2. Goldstein LS. Kinetochore structure and its role in chromosome orientation during the first meiotic division in male D. melanogaster. Cell. 1981 Sep;25(3):591-602.
  3. Goldstein LS. Mechanisms of chromosome orientation revealed by two meiotic mutants in Drosophila melanogaster. Chromosoma. 1980;78(1):79-111.
  1. Bunch TA, Goldstein LS. The conditional inhibition of gene expression in cultured Drosophila cells by antisense RNA. Nucleic Acids Res. 1989 Dec 11;17(23):9761-82.
  2. Dubreuil RR, Byers TJ, Sillman AL, Bar-Zvi D, Goldstein LS, Branton D. The complete sequence of Drosophila alpha-spectrin: conservation of structural domains between alpha-spectrins and alpha-actinin. J Cell Biol. 1989 Nov;109(5):2197-205.
  3. Byers TJ, Husain-Chishti A, Dubreuil RR, Branton D, Goldstein LS. Sequence similarity of the amino-terminal domain of Drosophila beta spectrin to alpha actinin and dystrophin. J Cell Biol. 1989 Oct;109(4 Pt 1):1633-41.
  4. Scholey JM, Heuser J, Yang JT, Goldstein LS. Identification of globular mechanochemical heads of kinesin. Nature. 1989 Mar 23;338(6213):355-7.
  5. Yang JT, Laymon RA, Goldstein LS. A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses. Cell. 1989 Mar 10;56(5):879-89.
  6. Kiehart DP, Lutz MS, Chan D, Ketchum AS, Laymon RA, Nguyen B, Goldstein LS. Identification of the gene for fly non-muscle myosin heavy chain: Drosophila myosin heavy chains are encoded by a gene family. EMBO J. 1989 Mar;8(3):913-22. Erratum in: EMBO J 1989 Jun;8(6):1896.
  7. Yang JT, Saxton WM, Goldstein LS. Isolation and characterization of the gene encoding the heavy chain of Drosophila kinesin. Proc Natl Acad Sci U S A. 1988 Mar;85(6):1864-8.
  8. Bunch TA, Grinblat Y, Goldstein LS. Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells. Nucleic Acids Res. 1988 Feb 11;16(3):1043-61.
  9. Dubreuil R, Byers TJ, Branton D, Goldstein LS, Kiehart DP. Drosophilia spectrin. I. Characterization of the purified protein. J Cell Biol. 1987 Nov;105(5):2095-102.
  10. Byers TJ, Dubreuil R, Branton D, Kiehart DP, Goldstein LS. Drosophila spectrin. II. Conserved features of the alpha-subunit are revealed by analysis of cDNA clones and fusion proteins. J Cell Biol. 1987 Nov;105(5):2103-10.
  11. Goldstein LS, Laymon RA, McIntosh JR. A microtubule-associated protein in Drosophila melanogaster: identification, characterization, and isolation of coding sequences. J Cell Biol. 1986 Jun;102(6):2076-87.
  1. Pesavento PA, Stewart RJ, Goldstein LS. Characterization of the KLP68D kinesin-like protein in Drosophila: possible roles in axonal transport. J Cell Biol. 1994 Nov;127(4):1041-8.
  2. Goldstein LS. Sources of information about the fly: where to look it up.
    Methods Cell Biol. 1994;44:3-12. Review.
  3. Lee JK, Coyne RS, Dubreuil RR, Goldstein LS, Branton D. Cell shape and interaction defects in alpha-spectrin mutants of Drosophila melanogaster. J Cell Biol. 1993 Dec;123(6 Pt 2):1797-809.
  4. Heck MM, Pereira A, Pesavento P, Yannoni Y, Spradling AC, Goldstein LS. The kinesin-like protein KLP61F is essential for mitosis in Drosophila. J Cell Biol. 1993 Nov;123(3):665-79.
  5. Gauger AK, Goldstein LS. The Drosophila kinesin light chain. Primary structure and interaction with kinesin heavy chain. J Biol Chem. 1993 Jun 25;268(18):13657-66.
  6. Stewart RJ, Thaler JP, Goldstein LS. Direction of microtubule movement is an intrinsic property of the motor domains of kinesin heavy chain and Drosophila ncd protein. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5209-13.
  7. Goldstein LS. Functional redundancy in mitotic force generation. J Cell Biol. 1993 Jan;120(1):1-3. Review.
  8. Goldstein LS. With apologies to sche herazade: tails of 1001 kinesin motors. Annu Rev Genet. 1993;27:319-51. Review.
  9. Goldstein LS, Vale RD. Cell biology. New cytoskeletal liaisons. Nature. 1992 Sep 17;359(6392):193-4.
  10. de Cuevas M, Tao T, Goldstein LS. Evidence that the stalk of Drosophila kinesin heavy chain is an alpha-helical coiled coil. J Cell Biol. 1992 Feb;116(4):957-65.
  11. Pereira A, Doshen J, Tanaka E, Goldstein LS. Genetic analysis of a Drosophila microtubule-associated protein.
    J Cell Biol. 1992 Jan;116(2):377-83.
  12. Goldstein LS. The kinesin superfamily: tails of functional redundancy. Trends Cell Biol. 1991 Oct;1(4):93-8.
  13. Stewart RJ, Pesavento PA, Woerpel DN, Goldstein LS. Identification and partial characterization of six members of the kinesin superfamily in Drosophila. Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8470-4.
  14. Goldstein LS, Vale RD. Motor proteins. A brave new world for dynein. Nature. 1991 Aug 15;352(6336):569-70.
  15. Dubreuil RR, Brandin E, Reisberg JH, Goldstein LS, Branton D. Structure, calmodulin-binding, and calcium-binding properties of recombinant alpha spectrin polypeptides. J Biol Chem. 1991 Apr 15;266(11):7189-93.
  16. Saxton WM, Hicks J, Goldstein LS, Raff EC. Kinesin heavy chain is essential for viability and neuromuscular functions in Drosophila, but mutants show no defects in mitosis. Cell. 1991 Mar 22;64(6):1093-102.
  17. McDonald HB, Stewart RJ, Goldstein LS. The kinesin-like ncd protein of Drosophila is a minus end-directed microtubule motor. Cell. 1990 Dec 21;63(6):1159-65.
  18. Irminger-Finger I, Laymon RA, Goldstein LS. Analysis of the primary sequence and microtubule-binding region of the Drosophila 205K MAP. J Cell Biol. 1990 Dec;111(6 Pt 1):2563-72.
  19. Block SM, Goldstein LS, Schnapp BJ. Bead movement by single kinesin molecules studied with optical tweezers.
    Nature. 1990 Nov 22;348(6299):348-52.
  20. Zhang P, Knowles BA, Goldstein LS, Hawley RS. A kinesin-like protein required for distributive chromosome segregation in Drosophila. Cell. 1990 Sep 21;62(6):1053-62.
  21. Yang JT, Saxton WM, Stewart RJ, Raff EC, Goldstein LS. Evidence that the head of kinesin is sufficient for force generation and motility in vitro. Science. 1990 Jul 6;249(4964):42-7.
  22. McDonald HB, Goldstein LS. Identification and characterization of a gene encoding a kinesin-like protein in Drosophila. Cell. 1990 Jun 15;61(6):991-1000.
  23. Vale RD, Goldstein LS. One motor, many tails: an expanding repertoire of force-generating enzymes.
    Cell. 1990 Mar 23;60(6):883-5. Review.
  24. Fyrberg EA, Goldstein LS. The Drosophila cytoskeleton.
    Annu Rev Cell Biol. 1990;6:559-96. Review.
  1. Sakowicz R, Farlow S, Goldstein LS. Cloning and expression of kinesins from the thermophilic fungus Thermomyces lanuginosus. Protein Sci. 1999 Dec;8(12):2705-10.
  2. Goldstein LS, Philp AV. The road less traveled: emerging principles of kinesin motor utilization.
    Annu Rev Cell Dev Biol. 1999;15:141-83. Review.
  3. Ray K, Perez SE, Yang Z, Xu J, Ritchings BW, Steller H, Goldstein LS. Kinesin-II is required for axonal transport of choline acetyltransferase in Drosophila. J Cell Biol. 1999 Nov 1;147(3):507-18.
  4. Rahman A, Kamal A, Roberts EA, Goldstein LS. Defective kinesin heavy chain behavior in mouse kinesin light chain mutants. J Cell Biol. 1999 Sep 20;146(6):1277-88.
  5. Bowman AB, Patel-King RS, Benashski SE, McCaffery JM, Goldstein LS, King SM. Drosophila roadblock and Chlamydomonas LC7: a conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis. J Cell Biol. 1999 Jul 12;146(1):165-80.
  6. Marszalek JR, Weiner JA, Farlow SJ, Chun J, Goldstein LS. Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B. J Cell Biol. 1999 May 3;145(3):469-79.
  7. Marszalek JR, Ruiz-Lozano P, Roberts E, Chien KR, Goldstein LS. Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5043-8.
  8. Xia Ch, Rahman A, Yang Z, Goldstein LS. Chromosomal localization reveals three kinesin heavy chain genes in mouse. Genomics. 1998 Sep 1;52(2):209-13.
  9. Rahman A, Friedman DS, Goldstein LS. Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins. J Biol Chem. 1998 Jun 19;273(25):15395-403. Erratum in: J Biol Chem 1998 Sep 11;273(37):24280.
  10. Gindhart JG Jr, Desai CJ, Beushausen S, Zinn K, Goldstein LS. Kinesin light chains are essential for axonal transport in Drosophila. J Cell Biol. 1998 Apr 20;141(2):443-54.
  11. Sakowicz R, Berdelis MS, Ray K, Blackburn CL, Hopmann C, Faulkner DJ, Goldstein LS. A marine natural product inhibitor of kinesin motors. Science. 1998 Apr 10;280(5361):292-5.
  12. Bloom GS, Goldstein LS. Cruising along microtubule highways: how membranes move through the secretory pathway. J Cell Biol. 1998 Mar 23;140(6):1277-80. Review. Erratum in: J Cell Biol 1998 May 18;141(4):1095.
  13. Yang Z, Goldstein LS. Characterization of the KIF3C neural kinesin-like motor from mouse.
    Mol Biol Cell. 1998 Feb;9(2):249-61.
  14. Wood KW, Sakowicz R, Goldstein LS, Cleveland DW. CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment. Cell. 1997 Oct 31;91(3):357-66.
  15. Yang Z, Hanlon DW, Marszalek JR, Goldstein LS. Identification, partial characterization, and genetic mapping of kinesin-like protein genes in mouse. Genomics. 1997 Oct 1;45(1):123-31.
  16. Tucker C, Goldstein LS. Probing the kinesin-microtubule interaction. J Biol Chem. 1997 Apr 4;272(14):9481-8.
  17. Pereira AJ, Dalby B, Stewart RJ, Doxsey SJ, Goldstein LS. Mitochondrial association of a plus end-directed microtubule motor expressed during mitosis in Drosophila. J Cell Biol. 1997 Mar 10;136(5):1081-90.
  18. Hanlon DW, Yang Z, Goldstein LS. Characterization of KIFC2, a neuronal kinesin superfamily member in mouse. Neuron. 1997 Mar;18(3):439-51.
  19. Lee JK, Brandin E, Branton D, Goldstein LS. alpha-Spectrin is required for ovarian follicle monolayer integrity in Drosophila melanogaster. Development. 1997 Jan;124(2):353-62.
  20. Gindhart JG Jr, Goldstein LS. Armadillo repeats in the SpKAP115 subunit of kinesin-II. Trends Cell Biol. 1996 Nov;6(11):415-6.
  21. Matthies HJ, McDonald HB, Goldstein LS, Theurkauf WE. Anastral meiotic spindle morphogenesis: role of the non-claret disjunctional kinesin-like protein. J Cell Biol. 1996 Jul;134(2):455-64.
  22. Sakowicz R, Goldstein LS. The muscle in kinesin. Nat Struct Biol. 1996 May;3(5):404-7.
  23. Barton NR, Goldstein LS. Going mobile: microtubule motors and chromosome segregation. Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):1735-42. Review.
  24. Desai CJ, Gindhart JG Jr, Goldstein LS, Zinn K. Receptor tyrosine phosphatases are required for motor axon guidance in the Drosophila embryo. Cell. 1996 Feb 23;84(4):599-609.
  25. Gindhart JG Jr, Goldstein LS. Tetratrico peptide repeats are present in the kinesin light chain.
    Trends Biochem Sci. 1996 Feb;21(2):52-3.
  26. Barton NR, Pereira AJ, Goldstein LS. Motor activity and mitotic spindle localization of the Drosophila kinesin-like protein KLP61F. Mol Biol Cell. 1995 Nov;6(11):1563-74.
  27. Afshar K, Barton NR, Hawley RS, Goldstein LS. DNA binding and meiotic chromosomal localization of the Drosophila nod kinesin-like protein. Cell. 1995 Apr 7;81(1):129-38.
  28. Goldstein LS. Structural features involved in force generation in the kinesin superfamily.
    Biophys J. 1995 Apr;68(4 Suppl):260S-265S; discussion 265S-266S. Review.
  29. Dalby B, Pereira AJ, Goldstein LS. An inverse PCR screen for the detection of P element insertions in cloned genomic intervals in Drosophila melanogaster. Genetics. 1995 Feb;139(2):757-66.
  30. Deng H, Lee JK, Goldstein LS, Branton D. Drosophila development requires spectrin network formation.
    J Cell Biol. 1995 Jan;128(1-2):71-9.
  1. Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, Endow SA, Goldstein LS, Goodson HV, Hirokawa N, Howard J, Malmberg RL, McIntosh JR, Miki H, Mitchison TJ, Okada Y, Reddy AS, Saxton WM, Schliwa M, Scholey JM, Vale RD, Walczak CE, Wordeman L. A standardized kinesin nomenclature. J Cell Biol. 2004 Oct 11;167(1):19-22.
  2. Guzik BW, Goldstein LS. Microtubule-dependent transport in neurons: steps towards an understanding of regulation, function and dysfunction. Curr Opin Cell Biol. 2004 Aug;16(4):443-50. Review.
  3. Gunawardena S, Goldstein LS. Cargo-carrying motor vehicles on the neuronal highway: transport pathways and neurodegenerative disease. J Neurobiol. 2004 Feb 5;58(2):258-71. Review.
  4. Goldstein LS. Do disorders of movement cause movement disorders and dementia? Neuron. 2003 Oct 9;40(2):415-25. Review.
  5. Gunawardena S, Her LS, Brusch RG, Laymon RA, Niesman IR, Gordesky-Gold B, Sintasath L, Bonini NM, Goldstein LS. Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron. 2003 Sep 25;40(1):25-40.
  6. Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, McMahon AP, Doucette W, Siwek D, Ferrante RJ, Brown RH Jr, Julien JP, Goldstein LS, Cleveland DW. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science. 2003 Oct 3;302(5642):113-7. Erratum in: Science. 2003 Oct 24;302(5645):568.
  7. Xia CH, Roberts EA, Her LS, Liu X, Williams DS, Cleveland DW, Goldstein LS. Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A.
    J Cell Biol. 2003 Apr 14;161(1):55-66. Epub 2003 Apr 7.
  8. Chang L, Jones Y, Ellisman MH, Goldstein LS, Karin M. JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins. Dev Cell. 2003 Apr;4(4):521-33.
  9. Lin F, Hiesberger T, Cordes K, Sinclair AM, Goldstein LS, Somlo S, Igarashi P. Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5286-91.
  10. Ji JY, Haghnia M, Trusty C, Goldstein LS, Schubiger G. A genetic screen for suppressors and enhancers of the Drosophila cdk1-cyclin B identifies maternal factors that regulate microtubule and microfilament stability.Genetics. 2002 Nov;162(3):1179-95.
  11. Kamal A, Goldstein LS. Principles of cargo attachment to cytoplasmic motor proteins. Curr Opin Cell Biol. 2002 Feb;14(1):63-8. Review.
    Kamal A, Almenar-Queralt A, LeBlanc JF, Roberts EA, Goldstein LS. Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP. Nature. 2001 Dec 6;414(6864):643-8.
  12. Goldstein LS. Molecular motors: from one motor many tails to one motor many tales. Trends Cell Biol. 2001 Dec;11(12):477-82. Review.
  13. Gunawardena S, Goldstein LS. Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila. Neuron. 2001 Nov 8;32(3):389-401.
  14. Blackburn CL, Hopmann C, Sakowicz R, Berdelis MS, Goldstein LS, Faulkner DJ. Adociasulfates 1-6, Inhibitors of Kinesin Motor Proteins from the Sponge Haliclona (aka Adocia) sp. J Org Chem. 1999 Jul 23;64(15):5565-5570.
  15. Peterman EJ, Sosa H, Goldstein LS, Moerner WE. Polarized fluorescence microscopy of individual and many kinesin motors bound to axonemal microtubules. Biophys J. 2001 Nov;81(5):2851-63.
  16. Almenar-Queralt A, Goldstein LS. Linkers, packages and pathways: new concepts in axonal transport.
    Curr Opin Neurobiol. 2001 Oct;11(5):550-7. Review.
  17. Yang Z, Roberts EA, Goldstein LS. Functional analysis of mouse kinesin motor Kif3C. Mol Cell Biol. 2001 Aug;21(16):5306-11.
  18. Goldstein LS. Kinesin molecular motors: transport pathways, receptors, and human disease.
    Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):6999-7003. Review.
  19. Sosa H, Peterman EJ, Moerner WE, Goldstein LS. ADP-induced rocking of the kinesin motor domain revealed by single-molecule fluorescence polarization microscopy. Nat Struct Biol. 2001 Jun;8(6):540-4.
  20. Yang Z, Roberts EA, Goldstein LS. Functional analysis of mouse C-terminal kinesin motor KifC2. Mol Cell Biol. 2001 Apr;21(7):2463-6.
  21. Goldstein LS. Transduction. When worlds collide--trafficking in JNK. Science. 2001 Mar 16;291(5511):2102-3.
  22. Goldstein LS, Theriot JA. Cytoskeleton. Curr Opin Cell Biol. 2001 Feb;13(1):17-8.
  23. Yang Z, Xia Ch, Roberts EA, Bush K, Nigam SK, Goldstein LS. Molecular cloning and functional analysis of mouse C-terminal kinesin motor KifC3. Mol Cell Biol. 2001 Feb;21(3):765-70.
  24. Kamal A, Stokin GB, Yang Z, Xia CH, Goldstein LS. Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. Neuron. 2000 Nov;28(2):449-59.
  25. Bowman AB, Kamal A, Ritchings BW, Philp AV, McGrail M, Gindhart JG, Goldstein LS. Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Cell. 2000 Nov 10;103(4):583-94.
  26. Marszalek JR, Liu X, Roberts EA, Chui D, Marth JD, Williams DS, Goldstein LS. Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors. Cell. 2000 Jul 21;102(2):175-87.
  27. Goldstein LS, Gunawardena S. Flying through the drosophila cytoskeletal genome.
    J Cell Biol. 2000 Jul 24;150(2):F63-8. Review.
  28. Yucel JK, Marszalek JD, McIntosh JR, Goldstein LS, Cleveland DW, Philp AV. CENP-meta, an essential kinetochore kinesin required for the maintenance of metaphase chromosome alignment in Drosophila. J Cell Biol. 2000 Jul 10;150(1):1-11.
  29. Kamal A, Goldstein LS. Connecting vesicle transport to the cytoskeleton. Curr Opin Cell Biol. 2000 Aug;12(4):503-8. Review.
  30. Goldstein LS, Yang Z. Microtubule-based transport systems in neurons: the roles of kinesins and dyneins.
    Annu Rev Neurosci. 2000;23:39-71. Review.
  31. Shah JV, Goldstein LS. Does motor protein intelligence contribute to neuronal polarity?
    Neuron. 2000 May;26(2):281-2.
  32. Dubreuil RR, Wang P, Dahl S, Lee J, Goldstein LS. Drosophila beta spectrin functions independently of alpha spectrin to polarize the Na,K ATPase in epithelial cells. J Cell Biol. 2000 May 1;149(3):647-56.
  33. Rubin GM, Yandell MD, Wortman JR, Gabor Miklos GL, Nelson CR, Hariharan IK, Fortini ME, Li PW, Apweiler R, Fleischmann W, Cherry JM, Henikoff S, Skupski MP, Misra S, Ashburner M, Birney E, Boguski MS, Brody T, Brokstein P, Celniker SE, Chervitz SA, Coates D, Cravchik A, Gabrielian A, Galle RF, Gelbart WM, George RA, Goldstein LS, Gong F, Guan P, Harris NL, Hay BA, Hoskins RA, Li J, Li Z, Hynes RO, Jones SJ, Kuehl PM, Lemaitre B, Littleton JT, Morrison DK, Mungall C, O'Farrell PH, Pickeral OK, Shue C, Vosshall LB, Zhang J, Zhao Q, Zheng XH, Lewis S. Comparative genomics of the eukaryotes. Science. 2000 Mar 24;287(5461):2204-15.
  34. Marszalek JR, Goldstein LS. Understanding the functions of kinesin-II. Biochim Biophys Acta. 2000 Mar 17;1496(1):142-50. Review.
  1. Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS, Cavalli V.Sunday driver interacts with two distinct classes of axonal organelles. J Biol Chem. 2009 Dec 11;284(50):34628-39.
  2. Shah SB, Nolan R, Davis E, Stokin GB, Niesman I, Canto I, Glabe C. Goldstein LS. Examination of potential mechanisms of amyloid-induced defects in neuronal transport. Neurobiol Dis. 2009 Oct;36(1):11-25.
  3. Falzone TL, Stokin GB, Lillo C, Rodrigues EM, Westerman EL, Williams DS, Goldstein LS. Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects. J Neurosci. 2009 May 6;29(18):5758-67.
  4. Her LS, Goldstein LS. Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin. J Neurosci. 2008 Dec 10;28(50):13662-72.
  5. Stokin GB, Almenar-Queralt A, Gunawardena S, Rodrigues EM, Falzone T, Kim J, Lillo C, Mount SL, Roberts EA, McGowan E, Williams DS, Goldstein LS. Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides. Hum Mol Genet. 2008 Nov 15;17(22):3474-86.
  6. Yamanaka K, Boillee S, Roberts EA, Garcia ML, McAlonis-Downes M, Mikse OR, Cleveland DW, Goldstein LS. Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice. Proc Natl Acad Sci U S A. 2008 May 27;105(21):7594-9. Epub 2008 May 20.
  7. Haghnia M, Cavalli V, Shah SB, Schimmelpfeng K, Brusch R, Yang G, Herrera C, Pilling A, Goldstein LS. Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment. Mol Biol Cell. 2007 Jun;18(6):2081-9. Epub 2007 Mar 14.
  8. Daley GQ, Ahrlund Richter L, Auerbach JM, Benvenisty N, Charo RA, Chen G, Deng HK, Goldstein LS, Hudson KL, Hyun I, Junn SC, Love J, Lee EH, McLaren A, Mummery CL, Nakatsuji N, Racowsky C, Rooke H, Rossant J, Schöler HR, Solbakk JH, Taylor P, Trounson AO, Weissman IL, Wilmut I, Yu J, Zoloth L. Ethics. The ISSCR guidelines for human embryonic stem cell research. Science. 2007 Feb 2;315(5812):603-4.
  9. Davis EA, Goldstein LS (2007) Directed differentiation of human embryonic stem cells into ectoderm: forebrain neurons. In: Human embryonic stem cells : the practical handbook(Sullivan, S. et al., eds), pp 327-336 Chichester, West Sussex, England ; Hoboken, NJ: John Wiley & Sons.
  10. Jimeno D, Feiner L, Lillo C, Teofilo K, Goldstein LS, Pierce EA, Williams DS. Analysis of kinesin-2 function in photoreceptor cells using synchronous Cre-loxP knockout of Kif3a with RHO-Cre. Invest Ophthalmol Vis Sci. 2006 Nov;47(11):5039-46.
  11. Duncan JE, Goldstein LS. The genetics of axonal transport and axonal transport disorders. PLoS Genet. 2006 Sep 29;2(9):e124. Review.
  12. Salehi A, Delcroix JD, Belichenko PV, Zhan K, Wu C, Valletta JS, Takimoto-Kimura R, Kleschevnikov AM, Sambamurti K, Chung PP, Xia W, Villar A, Campbell WA, Kulnane LS, Nixon RA, Lamb BT, Epstein CJ, Stokin GB, Goldstein LS, Mobley WC. Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration. Neuron. 2006 Jul 6;51(1):29-42.
  13. Stokin GB, Goldstein LS. Axonal transport and Alzheimer's disease. Annu Rev Biochem. 2006;75:607-27. Review.
  14. Stokin GB, Goldstein LS. Linking molecular motors to Alzheimer's disease. J Physiol Paris. 2006 Mar-May;99(2-3):193-200. Epub 2006 Feb 3. Review.
  15. Jimeno D, Lillo C, Roberts EA, Goldstein LS, Williams DS. Kinesin-2 and photoreceptor cell death: requirement of motor subunits. Exp Eye Res. 2006 Feb;82(2):351-3. Epub 2005 Dec 7.
  16. Cavalli V, Kujala P, Klumperman J, Goldstein LS. Sunday Driver links axonal transport to damage signaling. J Cell Biol. 2005 Feb 28;168(5):775-87.
  17. Stokin GB, Lillo C, Falzone TL, Brusch RG, Rockenstein E, Mount SL, Raman R, Davies P, Masliah E, Williams DS, Goldstein LS. Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science. 2005 Feb 25;307(5713):1282-8.
  18. Gunawardena S, Goldstein LS. Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways. Arch Neurol. 2005 Jan;62(1):46-51. Review.
  1. Neumann S, Campbell GE, Szpankowski L, Goldstein LS, Encalada SE. Characterizing the composition of molecular motors on moving axonal cargo using "cargo mapping" analysis. J Vis Exp. 2014 Oct 3; (92) doi: 10.3791/52029.
  2. Niederst ED, Reyna SM, Goldstein LS. Axonal amyloid precursor protein and its fragments undergo somatodendritic endocytosis and processing. Mol Biol Cell. 2014 Nov 12. pii: mbc.E14-06-1049.
  3. Liu Q, Waltz S, Woodruff G, Ouyang J, Israel MA, Herrera C, Sarsoza F, Tanzi RE, Koo EH, Ringman JM, Goldstein LS, Wagner SL, Yuan SH. Effect of potent γ-secretase modulator in human neurons derived From multiple Presenilin 1-Induced Pluripotent Stem Cell Mutant Carriers. JAMA Neurol. 2014 Dec 1;71(12):1481-9.
  4. Lu P, Woodruff G, Wang Y, Graham L, Hunt M, Wu D, Boehle E, Ahmad R, Poplawski G, Brock J, Goldstein LS, Tuszynski MH. Long-distance axonal growth from human induced pluripotent stem cells after spinal cord injury. Neuron. 2014 Aug 20;83(4):789-96.
  5. Encalada SE, Goldstein LS. Biophysical challenges to axonal transport: motor-cargo deficiencies and neurodegeneration. Annu Rev Biophys. 2014;43:141-69.
  6. Otero MG, Alloatti M, Cromberg LE, Almenar-Queralt A, Encalada SE, Pozo Devoto VM, Bruno L, Goldstein LS, Falzone TL. Fast axonal transport of the proteasome complex depends on membrane interaction and molecular motor function. J Cell Sci. 2014 Apr 1;127(Pt 7):1537-49.
  7. Almenar-Queralt A, Falzone TL, Shen Z, Lillo C, Killian RL, Arreola AS, Niederst ED, Ng KS, Kim SN, Briggs SP, Williams DS, Goldstein LS. UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport. J Neurosci. 2014 Feb 26;34(9):3320-39.
  8. Almenar-Queralt A, Kim SN, Benner C, Herrera CM, Kang DE, Garcia-Bassets I, Goldstein LS. Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation. J Biol Chem. 2013 Dec 6;288(49):35222-36.
  9. Woodruff G, Young JE, Martinez FJ, Buen F, Gore A, Kinaga J, Li Z, Yuan SH, Zhang K, Goldstein LS. The presenilin-1 ΔE9 mutation results in reduced γ-secretase activity, but not total loss of PS1 function, in isogenic human stem cells. Cell Rep. 2013 Nov 27;5(4):974-85.
  10. Gunawardena S, Yang G, Goldstein LS. Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo. Hum Mol Genet. 2013 Oct 6.
  11. Duncan JE, Lytle NK, Zuniga A, Goldstein LS. The microtubule regulatory protein stathmin Is required to maintain the integrity of axonal microtubules in Drosophila. PLoS One. 2013 Jun 26;8(6):e68324.
  12. Goldstein LSB. Unproven stem cell treatment cause for alarm. The San Diego Union-Tribune. May 15, 2013.
  13. Bianco P, Barker R, Brüstle O, Cattaneo E, Clevers H, Daley GQ, De Luca M, Goldstein LSB, Lindvall O, Mummery C, Robey PG, de Sousa e Brito CS, Smith A. Regulation of stem cell therapies under attack in Europe: for whom the bell tolls. The EMBO Journal. 2013 May 3;32:1489-1495.
  14. Haimes E, Skene L, Ballantyne AJ, Caulfield T, Goldstein LS, Hyun I, Kimmelman J, Robert JS, Roxland BE, Scott CT, Solbakk JH, Sugarman J, Taylor PL, Testa G; ISSCR. Position statement on the provision and procurement of human eggs for stem cell research. Cell Stem Cell. 2013 Mar 7;12(3):285-91.
  15. Goff DJ, Recart AC, Sadarangani A, Chun HJ, Barrett CL, Krajewska M, Leu H, Low-Marchelli J, Ma W, Shih AY, Wei J, Zhai D, Geron I, Pu M, Bao L, Chuang R, Balaian L, Gotlib J, Minden M, Martinelli G, Rusert J, Dao KH, Shazand K, Wentworth P, Smith KM, Jamieson CA, Morris SR, Messer K, Goldstein LS, Hudson TJ, Marra M, Frazer KA, Pellecchia M, Reed JC, Jamieson CH. A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. Cell Stem Cell. 2013 Mar 7;12(3):316-28.
  16. Weaver C, Leidel C, Szpankowski L, Farley NM, Shubeita GT, Goldstein LS. Endogenous GSK-3/shaggy regulates bidirectional axonal transport of the amyloid precursor protein. Traffic. 2013 Mar;14(3):295-308.
  17. Jiang Q, Crews LA, Barrett CL, Chun HJ, Court AC, Isquith JM, Zipeto MA, Goff DJ, Minden M, Sadarangani A, Rusert JM, Dao KH, Morris SR, Goldstein LS, Marra MA, Frazer KA, Jamieson CH. ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):1041-6.
  18. Goldstein LS. Axonal transport and neurodegenerative disease: Can we see the elephant? Prog Neurobiol. 2012 Dec;99(3):186-90.
  19. Goldstein LS. New frontiers in human cell biology and medicine: can pluripotent stem cells deliver? J Cell Biol. 2012 Nov 12;199(4):577-81.
  20. Rodrigues EM, Weissmiller AM, Goldstein LS. Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects. Hum Mol Genet. 2012 Nov 1;21(21):4587-601.
  21. Ordonez MP, Goldstein LS. Using human-induced pluripotent stem cells to model monogenic metabolic disorders of the liver. Semin Liver Dis. 2012 Nov;32(4):298-306.
  22. Young JE, Goldstein LS. Alzheimer's disease in a dish: promises and challenges of human stem cell models. Hum Mol Genet. 2012 Oct 15;21(R1):R82-9.
  23. Goldstein LS. An October call to arms: we are research! Mol Biol Cell. 2012 Sep;23(17):3279-80.
  24. Ordonez MP, Roberts EA, Kidwell CU, Yuan SH, Plaisted WC, Goldstein LS. Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1. Hum Mol Genet. 2012 Jun 15;21(12):2651-62.
  25. Szpankowski L, Encalada SE, Goldstein LS. Subpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles. Proc Natl Acad Sci USA. 2012 May 29;109(22):8582-7.
  26. Reis GF, Yang G, Szpankowski L, Weaver C, Shah SB, Robinson JT, Hays TS, Danuser G, Goldstein LS. Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila. Mol Biol Cell. 2012 May;23(9):1700-14.
  27. Israel MA, Yuan SH, Bardy C, Reyna SM, Mu Y, Herrera C, Hefferan MP, Van Gorp S, Nazor KL, Boscolo FS, Carson CT, Laurent LC, Marsala M, Gage FH, Remes AM, Koo EH, Goldstein LS. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature. 2012 Jan 25;482(7384):216-20.
  28. Killian RL, Flippin JD, Herrera CM, Almenar-Queralt A, Goldstein LS. Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. PLoS One. 2012;7(1):e29755. Epub 2012 Jan 17.
  29. Goldstein LS. In the trenches: lessons for scientists from California's Proposition 71 campaign. Mol Biol Cell. 2011 Nov;22(21):3943-4.
  30. Dequach JA, Yuan SH, Goldstein LS, Christman KL.Decellularized Porcine Brain Matrix for Cell Culture and Tissue Engineering Scaffolds. Tissue Eng Part A. 2011 Nov;17(21-22):2583-92.
  31. Henthorn KS, Roux MS, Herrera C, Goldstein LS. A Role for Kinesin Heavy Chain in Controlling Vesicle Transport into Dendrites in Drosophila. Mol Biol Cell. 2011 Nov;22(21):4038-46.
  32. Israel MA, Goldstein LS. Capturing Alzheimer's disease genomes with induced pluripotent stem cells: prospects and challenges. Genome Med. 2011 Jul 27;3(7):49.
  33. Yuan SH, Martin J, Elia J, Flippin J, Paramban RI, Hefferan MP, Vidal JG, Mu Y, Killian RL, Israel MA, Emre N, Marsala S, Marsala M, Gage FH, Goldstein LS, Carson CT. Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells. PLoS One. 2011 Mar 2;6(3):e17540.
  34. Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, Ruiz S, Wilbert ML, Yu J, Kirkness EF, Izpisua Belmonte JC, Rossi DJ, Thomson JA, Eggan K, Daley GQ, Goldstein LS, Zhang K. Somatic coding mutations in human induced pluripotent stem cells. Nature. 2011 Mar 3;471(7336):63-7.
  35. Encalada SE, Szpankowski L, Xia CH, Goldstein LS. Stable Kinesin and Dynein assemblies drive the axonal transport of Mammalian prion protein vesicles. Cell. 2011 Feb 18;144(4):551-65.
  36. Kim JE, O'Sullivan ML, Sanchez CA, Hwang M, Israel MA, Brennand K, Deerinck TJ, Goldstein LS, Gage FH, Ellisman MH, Ghosh A. Investigating synapse formation and function using human pluripotent stem cell-derived neurons. Proc Natl Acad Sci U S A. 2011 Jan 28.
  37. Goldstein LS. Unconventional allies: interdisciplinary approaches to science policy and funding. Trends Cell Biol. 2010 Dec; 20(12):695-8.
  38. Falzone TL, Gunawardena S, McCleary D, Reis GF, Goldstein LS. Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies. Hum Mol Genet. 2010 Nov 15;19(22):4399-408
  39. Taylor PL, Barker RA, Blume KG, Cattaneo E, Colman A, Deng H, Edgar H, Fox IJ, Gerstle C, Goldstein LS, High KA, Lyall A, Parkman R, Pitossi FJ, Prentice ED, Rooke HM, Sipp DA, Srivastava A, Stayn S, Steinberg GK, Wagers AJ, Weissman IL. Patients beware: commercialized stem cell treatments on the web. Cell Stem Cell. 2010 Jul 2;7(1):43-9.
  40. Lian I, Kim J, Okazawa H, Zhao J, Zhao B, Yu J, Chinnaiyan A, Israel MA, Goldstein LS, Abujarour R, Ding S, Guan KL. The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation. Genes Dev. 2010 Jun 1;24(11):1106-18.
  41. Goldstein L.S.B., Schneider M. Stem Cells For Dummies. For Dummies (2010).
  1. pubmedComing soon