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Cellular & Molecular Medicine Courses

The faculty in the Department of Cellular & Molecular Medicine teach in a wide variety of graduate and medical school courses involving cell biology and molecular biology.

Required BMS Graduate Courses:

BMS-200 From the Molecule to the Organism
Course Director: Steve Dowdy, Ph.D., and Alexandra Newton, Ph.D.
Theme Leader Lecturers: Fu, Emr, Hamilton, Cleveland, Spector
BMS-200 Course Syllabus in .PDF Format

BIOM-201 Seminar in Biomedical Research
Course Director: Bruce Hamilton (Medicine and CMM)
Course Faculty: Steven Chessler (Medicine), Seth Field (Medicine), Karen Oegema (CMM), David Williams (Pharmacology), Huilin Zhou (CMM)

Required Medical Student Courses:

CBB Core: Cellular and Molecular Basis of Disease
Course Directors: Marilyn Farquhar, Ph.D. and Deborah Spector, Ph.D.
CBB Core Cell Biology Course Syllabus in .PDF Format

Elective Graduate Courses:

CMM250 - Core course in Stem Cell Biology, Medicine, and Ethics
Course Director: Catriona Jamieson, MD Ph.D.
Lectures and discussions on the basic, translational, and clinical elements of stem cell biology. Topics include identification, purification, and properties of stem cells; uses in animal models; clinical application to systems and diseases; ethical, economic, and social issues.
Offered in Winter term

CMM251 - Laboratory course for Human Embryonic Stem Cell Research
Course Director: Karl Willert, Ph.D.
Laboratory methods for research with hESCs; available lines, culture conditions; markers and karyotypes; thawing and plating; manual and enzymatic passaging; maintenance of hESCs and EBs; differentiation protocols; gene transduction; harvesting; infection; fixing and staining; feeding, confocal and automated microscopy.
Offered occasionally

CMM252 - Current literature in Stem Cell Biology, Medicine, and Ethics
Course Director: Karl Willert, Ph.D.
The course explores in Journal Club format the latest literature in theory, research method, and clinical application of stem cell biology and medicine, with a strong emphasis on human embryonic stem cell approaches.
Offered in Spring term and Fall term

BIOM 240: Method & Logic in Biological Research
Method & Logic in Cell Biology Research, BIOM 240

Essentials of Glycobiology (BMS 222/CHEM 237/BIO 236/MED 225)
Course Director: Jeff Esko, Ph.D. and Ajit Varki, M.D./Ph.D.
The primary aim of this course is to provide an easy-to-understand, succinct, and current overview of the fundamental facts, concepts, and methods in glycobiology. The course is supported by the textbook, Essentials of Glycobiology which was authored and edited by the lecturers. The book provides background material for discussion. More detailed information will be provided to help guide the reader into literature of the field. Background requirements: Coursework in cell biology and biochemistry. Required Text: The 2nd edition of Essentials of Glycobiology, Varki A, Cummings R, Esko J, Freeze H, Stanley, P., Bertozzi, C., Hart G, and Etzler, M. (editors). 2008 Cold Spring Harbor Laboratory Press, New York is currently in press. Chapters will be available to participants in the course. Grading will be based on regular attendance and active participation in class discussion. Credit: 4 units. Letter grade and S/U grading options available.

Current Literature in Glycobiology (MED 246)
Course Director(s): Ajit Varki/Jeff Esko/Pascal Gagneux
Current Literature in Glycobiology is a one-credit elective that provides a forum for informally discussing current papers in glycobiology research. Topics include glycan chemistry, biochemistry, genetics, cell biology, and molecular biology in animals, plants, and microtubes, as well as medical aspects of glycobiology. Typically, 20-25 students, post-docs, and faculty attend the meeting on a weekly basis. Credit: 1 unit.

Reading Group Workshop (SOM 204), Glycobiology and Medicine
Course Director: Jeff Esko, Ph.D.
The purpose of the reading group is to familiarize first year medical students with the field of glycobiology as it relates to human health and disease. Topics include research papers and review articles that focus on glycosylation and blood group antigens, xenotransplantation, selectin-mediated leukocyte adhesion, inflammation, innate immunity, human in-born errors of metabolism and mutant mice, receptors that mediate microbial adhesion and ulcer formation, and tumor cell antigens. Recent advances in these areas suggest novel therapeutic approaches for treating human disease. Students make semi-formal presentations of current papers in order to develop an appreciation of the field, critical thinking skills, and improved public speaking. Credit: 1 unit.

Cancer Biology Journal Club (CMM 220)
Course Director: Steve Dowdy, Ph.D.
The Cancer Biology Journal Club is a student presentation format that focuses on and critically reviews a recent paper of importance in the broad field of cancer biology. Students will be expected to prepare a powerpoint presentation on the paper plus a 5-10 minute review of the field taken from a recent review(s) and/or prior publications from the paper's group. Students will be evaluated in a pass/no pass grading system. Students will be coached on their scientific speaking style with emphasis on speaking to the audience, avoidance of slang, correct use of laser pointer, etc.; however, students will not be graded on speaking style as this aspect of the course is intended to be a learning exercise.

Genetics Journal Club (BIOM 242)
Course Director: Bruce Hamilton, Ph.D.
Intended for graduate students interested in principles of classical and molecular genetics.Will attend weekly genetics seminar and participate in didactic/discussion preparatory session.

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"Cell Biology and Molecular Biology Research to Understand Human Disease."