Recent Relevant Publications
Thacker, B.E., Thorne, K.J., Cartwright, C., Park, J., Glass, K., Chea, A., Kellman, B.P., Lewis, N.E., Wang, Z., Di Nardo, A., Sharfstein, S.T., Jeske, W., Walenga, J., Hogwood, J., Gray, E., Mulloy, B., Esko, J.D. and Glass, C.A. (2022) Multiplex genome editing of mammalian cells for producing recombinant heparin. Metab. Eng. 70:155-165. PMID:35038554
Yan, W., Cao, M., Ruan, X., Jiang, L., Lee, S., Lemanek, A., Ghassemian, M., Pizzo, D.P., Wan, Y., Qiao, Y., Chin, A.R., Duggan, E., Wang, D., Nolan, J.P., Esko, J.D., Schenk, S. and Wang, S.E. (2022) Cancer-cell-secreted miR-122 suppresses O-GlcNAcylation to promote skeletal muscle proteolysis. Nat. Cell. Biol. 24:793-804. PMID:35469018 PMCID:9107513
Tao, C., Makrides, N., Chuang, J.Z., Wu, Y., Brooks, S.E., Esko, J.D., Sung, C.H. and Zhang, X. (2022) Chondroitin sulfate enhances the barrier function of basement membrane assembled by heparan sulfate. Development 149:dev200569. PMID:35608020 PMCID:9107513
Tillo, M., Lamanna, W.C., Dwyer, C.A., Sandoval, D.R., Pessentheiner, A.R., Al-Azzam, N., Sarrazin, S., Gonzales, J.C., Kan, S.H., Andreyev, A.Y., Schultheis, N., Thacker, B.E., Glass, C.A., Dickson, P.I., Wang, R.Y., Selleck, S.B., Esko, J.D. and Gordts, P.L.S.M. Impaired Mitophagy in Sanfilippo A mice Causes Hypertriglyceridemia and Brown Adipose Tissue Activation. (2022) J Biol Chem. 21:102159. PMID: 35750212 PMCID:9364035
Sorrentino, J.T., Golden, G.J., Morris, C., Painter, C., Nizet, V., Campos, A.R., Smith, J.W., Karlsson, C., Malmström, J., Lewis, N.E., Esko, J.D. and Toledo, A.G. (2022) Vascular proteome responses precede organ dysfunction in a murine model of Staphylococcus aureus bacteremia (2022) mSystems 7:e0039522. PMID:35913192 PMCID:9426442
Al Nakouzi, N., Wang, C., Oo, H.Z., Nelepcu, I., Lallous, N., Spliid, C., Khazamipour, N., Lo, J., Truong, S., Collins, C., Hui, D., Esfandnia, S., Adomat, H., Mandel-Clausen, T., Gustavsson, T., Choudhary, S., Dagil, R., Corey, E., Wang, Y., Chauchereau, A., Fazli, L., Esko, J., Salanti, A., Nelson, P., Gleave, M. and Daugaard, M. (2022) Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer Nat. Commun. 13:4760. PMID:35963852 PMCID:9376089
SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling (2022) Biering, S.B., Gomes de Sousa, F.T., Tjang, L.V., Pahmeier, F., Zhu, C., Ruan, R., Blanc, S.F., Patel, T.S., Worthington, C.M., Glasner, D.R., Castillo-Rojas, B., Servellita, V., Lo, N.T.N., Wong, M.P., Warnes, C.M., Sandoval, D.R., Clausen, T.M., Santos, Y.A., Fox, D.M., Ortega, V., Näär, A.M., Baric, R.S., Stanley, S,A., Aguilar, H.C., Esko, J.D., Chiu, C.Y., Pak, J.E., Beatty, P.R. and Harris, E. Nat. Commun. 13:7630. PMID:36494335 PMCID:PMC9734751
Sørensen, D., Büll, C., Madsen, T., Lira-Navarrete, E., Clausen, T., Clark, A., Garretson, A., Karlsson, R., Pijnenborg, J., Yin, X., Miller, R., Chanda, S., Boltje, T., Schjoldager, K., Vakhrushev, S., Halim, A., Esko, J.D., Carlin, A., Hurtado-Guerrero, R., Weigert, R., Clausen, H. and Narimatsu, Y. (2023) Identification of global inhibitors of cellular glycosylation. Nat. Commun. 14:948. PMID:36804936 PMCID:9941569
Wang, X., Ramos, R., Phan, A.Q., Yamaga, K., Flesher, J.L., Jiang, S., Oh, J.W., Jin, S., Jahid, S., Kuan, C.H., Nguyen, T.K., Liang, H.Y., Shettigar. N.U., Hou, R., Tran, K.H., Nguyen, A., Vu, K.N., Phung, J.L., Ingal, J.P., Levitt, K.M., Cao, X., Liu, Y., Deng, Z., Taguchi, N., Scarfone, V.M., Wang, G., Paolilli, K.N., Wang, X., Guerrero-Juarez, C.F., Davis, R.T., Greenberg, E.N., Ruiz-Vega, R., Vasudeva, P., Murad, R., Widyastuti, L.H.P., Lee, H.L., McElwee, K.J., Gadeau, A.P., Lawson, D.A., Andersen, B., Mortazavi, A., Yu, Z., Nie, Q., Kunisada, T., Karin, M., Tuckermann, J., Esko, J.D., Ganesan, A.K., Li, J. and Plikus, M.V. (2023) Signalling by senescent melanocytes hyperactivates hair growth Nature 618:808-817. PMID: 37344645
Pihl, J., Clausen, T.M., Zhou, J., Krishnan, N., Ørum-Madsen, M.S., Gustavsson, T., Dagil. R., Daugaard, M., Choudhary, S., Foged, C., Esko, J.D., Zhang, L., Fang, R.H. and Salanti, A. (2023) Malaria biomimetic for tumor targeted drug delivery. ACS Nano. 17:13500-13509. PMID: 37435892
Aguilar-Calvo, P., Malik, A., Sandoval, D.R., Barback, C., Orrù, C.D., Standke, H.G., Thomas, O.R., Dwyer, C.A., Pizzo, D.P., Bapat, J., Soldau, K., Ogawa, R., Riley, M.B., Nilsson, K.P.R., Kraus, A., Caughey, B., Iliff, J.J., Vera, D.R., Esko, J.D. and Sigurdson, C.J. (2023) Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection. PLoS Pathog. 19:e1011487. PMID:37747931
Toledo, A.G., Bratanis, E., Velásquez, E., Chowdhury, S., Olofsson, B., Sorrentino, J.T., Karlsson, C., Lewis, N.E., Esko, J.D., Collin, M., Shannon, O., Malmström, J. (2023) Pathogen-driven degradation of endogenous and therapeutic antibodies during streptococcal infections. Nat. Commun. 14:6693. PMID:37872209
Sreekumar, A., Lu, M., Choudhury, B., Pan, T.C., Pant, D.K., Lawrence-Paul, M.R., Sterner, C.J., Belka, G.K., Toriumi, T., Benz, B.A., Escobar-Aguirre, M., Marino, F.E., Esko, J.D. and Chodosh. L.A. (2023) B3GALT6 promotes dormant breast cancer cell survival and recurrence by enabling heparan sulfate-mediated FGF signaling. Cancer Cell. S1535-6108(23)00399-9.PMID: 38065100