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Department of Cellular & Molecular Medicine CMM
  1. Department of Cellular and Molecular Medicine
  2. Research
  3. Labs
  4. Ferro-Novick Lab
  5. Publications

Publications

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Chen S, Roberts MA, Chen CY, Markmiller S, Wei HG, Yeo GW, Granneman JG, Olzmann JA, Ferro-Novick S. VPS13A and VPS13C Influence Lipid Droplet Abundance. Contact (Thousand Oaks). 2022 Jan-Dec;5:25152564221125613. doi: 10.1177/25152564221125613. eCollection 2022 Jan-Dec. PubMed PMID: 36147729; PubMed Central PMCID: PMC9491623.

Liu D, Mari M, Li X, Reggiori F, Ferro-Novick S, Novick P. ER-phagy requires the assembly of actin at sites of contact between the cortical ER and endocytic pits. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6). doi: 10.1073/pnas.2117554119. PubMed PMID: 35101986; PubMed Central PMCID: PMC8833162.

Parashar S, Chidambaram R, Chen S, Liem CR, Griffis E, Lambert GG, Shaner NC, Wortham M, Hay JC, Ferro-Novick S. Endoplasmic reticulum tubules limit the size of misfolded protein condensates. Elife. 2021 Sep 1;10. doi: 10.7554/eLife.71642. PubMed PMID: 34467852; PubMed Central PMCID: PMC8486381.

Ferro-Novick S, Reggiori F, Brodsky JL. ER-Phagy, ER Homeostasis, and ER Quality Control: Implications for Disease. Trends Biochem Sci. 2021 Aug;46(8):630-639. doi: 10.1016/j.tibs.2020.12.013. Epub 2021 Jan 25. Review. PubMed PMID: 33509650; PubMed Central PMCID: PMC8286283.

Chen S, Mari M, Parashar S, Liu D, Cui Y, Reggiori F, Novick PJ, Ferro-Novick S. Vps13 is required for the packaging of the ER into autophagosomes during ER-phagy. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18530-18539. doi: 10.1073/pnas.2008923117. Epub 2020 Jul 20. PubMed PMID: 32690699; PubMed Central PMCID: PMC7414049. 

Cui Y, Parashar S, Zahoor M, Needham PG, Mari M, Zhu M, Chen S, Ho HC, Reggiori F, Farhan H, Brodsky JL, Ferro-Novick S. A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation. Science. 2019 Jul 5;365(6448):53-60. doi: 10.1126/science.aau9263. PubMed PMID: 31273116; PubMed Central PMCID: PMC7062386.

2023

Liu D, Ferro-Novick S, Novick P. Actin assembly at sites of contact between the cortical ER and endocytic pits promotes ER autophagy. Autophagy. 2023 Jan;19(1):358-359. doi: 10.1080/15548627.2022.2074614. Epub 2022 May 15. PubMed PMID: 35532158; PubMed Central PMCID: PMC9809928.

2022

Chen S, Roberts MA, Chen CY, Markmiller S, Wei HG, Yeo GW, Granneman JG, Olzmann JA, Ferro-Novick S. VPS13A and VPS13C Influence Lipid Droplet Abundance. Contact (Thousand Oaks). 2022 Jan-Dec;5:25152564221125613. doi: 10.1177/25152564221125613. eCollection 2022 Jan-Dec. PubMed PMID: 36147729; PubMed Central PMCID: PMC9491623.

Novick P, Liu D, Ferro-Novick S. Autophagy of the ER requires actin assembly driven by the interaction of ER with endocytic pits. Contact (Thousand Oaks). 2022 Jan-Dec;5. doi: 10.1177/25152564221093215. Epub 2022 Apr 13. PubMed PMID: 37102157; PubMed Central PMCID: PMC10129067.

Parashar S, Ferro-Novick S. Architecture of the endoplasmic reticulum plays a role in proteostasis. Autophagy. 2022 Apr;18(4):937-938. doi: 10.1080/15548627.2022.2030175. Epub 2022 Jan 31. PubMed PMID: 35100068; PubMed Central PMCID: PMC9037456.

Liu D, Mari M, Li X, Reggiori F, Ferro-Novick S, Novick P. ER-phagy requires the assembly of actin at sites of contact between the cortical ER and endocytic pits. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6). doi: 10.1073/pnas.2117554119. PubMed PMID: 35101986; PubMed Central PMCID: PMC8833162.

Ferro-Novick S, Rapoport TA, Schekman R, editors. Perspectives in Biology: The Endoplasmic Reticulum New York, NY: Cold Spring Harbor Laboratory Press; 2022.

2021

Parashar S, Chidambaram R, Chen S, Liem CR, Griffis E, Lambert GG, Shaner NC, Wortham M, Hay JC, Ferro-Novick S. Endoplasmic reticulum tubules limit the size of misfolded protein condensates. Elife. 2021 Sep 1;10. doi: 10.7554/eLife.71642. PubMed PMID: 34467852; PubMed Central PMCID: PMC8486381.

Ferro-Novick S, Reggiori F, Brodsky JL. ER-Phagy, ER Homeostasis, and ER Quality Control: Implications for Disease. Trends Biochem Sci. 2021 Aug;46(8):630-639. doi: 10.1016/j.tibs.2020.12.013. Epub 2021 Jan 25. Review. PubMed PMID: 33509650; PubMed Central PMCID: PMC8286283.

Wang J, Wang S, Ferro-Novick S. Methods for Assessing the Regulation of a Kinase by the Rab GTPase Ypt1. Methods Mol Biol. 2021;2293:201-211. doi: 10.1007/978-1-0716-1346-7_14. PubMed PMID: 34453719; PubMed Central PMCID: PMC8893604.

2020

Chen S, Mari M, Parashar S, Liu D, Cui Y, Reggiori F, Novick PJ, Ferro-Novick S. Vps13 is required for the packaging of the ER into autophagosomes during ER-phagy. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18530-18539. doi: 10.1073/pnas.2008923117. Epub 2020 Jul 20. PubMed PMID: 32690699; PubMed Central PMCID: PMC7414049. 

2019

Cui Y, Parashar S, Ferro-Novick S. A new role for a COPII cargo adaptor in autophagy. Autophagy. 2020 Feb;16(2):376-378. doi: 10.1080/15548627.2019.1699347. Epub 2019 Dec 3. PubMed PMID: 31795809; PubMed Central PMCID: PMC6984482.

Cui Y, Parashar S, Zahoor M, Needham PG, Mari M, Zhu M, Chen S, Ho HC, Reggiori F, Farhan H, Brodsky JL, Ferro-Novick S. A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation. Science. 2019 Jul 5;365(6448):53-60. doi: 10.1126/science.aau9263. PubMed PMID: 31273116; PubMed Central PMCID: PMC7062386.

2018

Chen S, Cui Y, Parashar S, Novick PJ, Ferro-Novick S. ER-phagy requires Lnp1, a protein that stabilizes rearrangements of the ER network. Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6237-E6244. doi: 10.1073/pnas.1805032115. Epub 2018 Jun 18. PubMed PMID: 29915089; PubMed Central PMCID: PMC6142256.

2017

Yuan H, Davis S, Ferro-Novick S, Novick P. Rewiring a Rab regulatory network reveals a possible inhibitory role for the vesicle tether, Uso1. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8637-E8645. doi: 10.1073/pnas.1708394114. Epub 2017 Sep 25. PubMed PMID: 28973856; PubMed Central PMCID: PMC5642711.

Wang J, Davis S, Zhu M, Miller EA, Ferro-Novick S. Autophagosome formation: Where the secretory and autophagy pathways meet. Autophagy. 2017 May 4;13(5):973-974. doi: 10.1080/15548627.2017.1287657. Epub 2017 Feb 15. Review. PubMed PMID: 28287860; PubMed Central PMCID: PMC5446067.

Farhan H, Kundu M, Ferro-Novick S. The link between autophagy and secretion: a story of multitasking proteins. Mol Biol Cell. 2017 May 1;28(9):1161-1164. doi: 10.1091/mbc.E16-11-0762. Review. PubMed PMID: 28468940; PubMed Central PMCID: PMC5415012.

Davis S, Wang J, Ferro-Novick S. Crosstalk between the Secretory and Autophagy Pathways Regulates Autophagosome Formation. Dev Cell. 2017 Apr 10;41(1):23-32. doi: 10.1016/j.devcel.2017.03.015. Review. PubMed PMID: 28399396; PubMed Central PMCID: PMC5493037.

2016

Davis S, Wang J, Zhu M, Stahmer K, Lakshminarayan R, Ghassemian M, Jiang Y, Miller EA, Ferro-Novick S. Sec24 phosphorylation regulates autophagosome abundance during nutrient deprivation. Elife. 2016 Nov 18;5. doi: 10.7554/eLife.21167. PubMed PMID: 27855785; PubMed Central PMCID: PMC5148606.

Ding J, Segarra VA, Chen S, Cai H, Lemmon SK, Ferro-Novick S. Auxilin facilitates membrane traffic in the early secretory pathway. Mol Biol Cell. 2016 Jan 1;27(1):127-36. doi: 10.1091/mbc.E15-09-0631. Epub 2015 Nov 4. PubMed PMID: 26538028; PubMed Central PMCID: PMC4694752.

2015

Casey AK, Chen S, Novick P, Ferro-Novick S, Wente SR. Nuclear pore complex integrity requires Lnp1, a regulator of cortical endoplasmic reticulum. Mol Biol Cell. 2015 Aug 1;26(15):2833-44. doi: 10.1091/mbc.E15-01-0053. Epub 2015 Jun 3. PubMed PMID: 26041935; PubMed Central PMCID: PMC4571342.

Wang J, Davis S, Menon S, Zhang J, Ding J, Cervantes S, Miller E, Jiang Y, Ferro-Novick S. Ypt1/Rab1 regulates Hrr25/CK1δ kinase activity in ER-Golgi traffic and macroautophagy. J Cell Biol. 2015 Jul 20;210(2):273-85. doi: 10.1083/jcb.201408075. PubMed PMID: 26195667; PubMed Central PMCID: PMC4508898.

Davis S, Ferro-Novick S. Ypt1 and COPII vesicles act in autophagosome biogenesis and the early secretory pathway. Biochem Soc Trans. 2015 Feb;43(1):92-6. doi: 10.1042/BST20140247. PubMed PMID: 25619251.

Chen S, Desai T, McNew JA, Gerard P, Novick PJ, Ferro-Novick S. Lunapark stabilizes nascent three-way junctions in the endoplasmic reticulum. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):418-23. doi: 10.1073/pnas.1423026112. Epub 2014 Dec 29. PubMed PMID: 25548161; PubMed Central PMCID: PMC4299238.

Wang J, Cervantes S, Davis S, Ferro-Novick S. Identifying a Rab effector on the macroautophagy pathway. Methods Mol Biol. 2015;1298:117-25. doi: 10.1007/978-1-4939-2569-8_10. PubMed PMID: 25800837.

2014

Wang J, Tan D, Cai Y, Reinisch KM, Walz T, Ferro-Novick S. A requirement for ER-derived COPII vesicles in phagophore initiation. Autophagy. 2014 Apr;10(4):708-9. doi: 10.4161/auto.28103. Epub 2014 Feb 12. PubMed PMID: 24561915; PubMed Central PMCID: PMC4091162.

2013

Ferro-Novick S, Brose N. Nobel 2013 Physiology or medicine: Traffic control system within cells. Nature. 2013 Dec 5;504(7478):98. doi: 10.1038/504098a. PubMed PMID: 24305158.

Tan D, Cai Y, Wang J, Zhang J, Menon S, Chou HT, Ferro-Novick S, Reinisch KM, Walz T. The EM structure of the TRAPPIII complex leads to the identification of a requirement for COPII vesicles on the macroautophagy pathway. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19432-7. doi: 10.1073/pnas.1316356110. Epub 2013 Nov 11. PubMed PMID: 24218626; PubMed Central PMCID: PMC3845172.

Li X, Ferro-Novick S, Novick P. Different polarisome components play distinct roles in Slt2p-regulated cortical ER inheritance in Saccharomyces cerevisiae. Mol Biol Cell. 2013 Oct;24(19):3145-54. doi: 10.1091/mbc.E13-05-0268. Epub 2013 Aug 7. PubMed PMID: 23924898; PubMed Central PMCID: PMC3784387.

Bhandari D, Zhang J, Menon S, Lord C, Chen S, Helm JR, Thorsen K, Corbett KD, Hay JC, Ferro-Novick S. Sit4p/PP6 regulates ER-to-Golgi traffic by controlling the dephosphorylation of COPII coat subunits. Mol Biol Cell. 2013 Sep;24(17):2727-38. doi: 10.1091/mbc.E13-02-0114. Epub 2013 Jul 17. PubMed PMID: 23864707; PubMed Central PMCID: PMC3756924.

Chen S, Novick P, Ferro-Novick S. ER structure and function. Curr Opin Cell Biol. 2013 Aug;25(4):428-33. doi: 10.1016/j.ceb.2013.02.006. Epub 2013 Mar 13. Review. PubMed PMID: 23478217; PubMed Central PMCID: PMC5614462.

Wang J, Menon S, Yamasaki A, Chou HT, Walz T, Jiang Y, Ferro-Novick S. Ypt1 recruits the Atg1 kinase to the preautophagosomal structure. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9800-5. doi: 10.1073/pnas.1302337110. Epub 2013 May 28. PubMed PMID: 23716696; PubMed Central PMCID: PMC3683756.

Lord C, Ferro-Novick S, Miller EA. The highly conserved COPII coat complex sorts cargo from the endoplasmic reticulum and targets it to the golgi. Cold Spring Harb Perspect Biol. 2013 Feb 1;5(2). doi: 10.1101/cshperspect.a013367. Review. PubMed PMID: 23378591; PubMed Central PMCID: PMC3552504.

Ferro-Novick S, Rapoport TA, Schekman R, editors. Perspectives in Biology: The Endoplasmic Reticulum New York, NY: Cold Spring Harbor Laboratory Press; 2013.

2012

Chen S, Novick P, Ferro-Novick S. ER network formation requires a balance of the dynamin-like GTPase Sey1p and the Lunapark family member Lnp1p. Nat Cell Biol. 2012 Jun 24;14(7):707-16. doi: 10.1038/ncb2523. PubMed PMID: 22729086; PubMed Central PMCID: PMC3389217.

Lee JH, Silhavy JL, Lee JE, Al-Gazali L, Thomas S, Davis EE, Bielas SL, Hill KJ, Iannicelli M, Brancati F, Gabriel SB, Russ C, Logan CV, Sharif SM, Bennett CP, Abe M, Hildebrandt F, Diplas BH, Attié-Bitach T, Katsanis N, Rajab A, Koul R, Sztriha L, Waters ER, Ferro-Novick S, Woods CG, Johnson CA, Valente EM, Zaki MS, Gleeson JG. Evolutionarily assembled cis-regulatory module at a human ciliopathy locus. Science. 2012 Feb 24;335(6071):966-9. doi: 10.1126/science.1213506. Epub 2012 Jan 26. PubMed PMID: 22282472; PubMed Central PMCID: PMC3671610.

2011

Chen S, Cai H, Park SK, Menon S, Jackson CL, Ferro-Novick S. Trs65p, a subunit of the Ypt1p GEF TRAPPII, interacts with the Arf1p exchange factor Gea2p to facilitate COPI-mediated vesicle traffic. Mol Biol Cell. 2011 Oct;22(19):3634-44. doi: 10.1091/mbc.E11-03-0197. Epub 2011 Aug 3. PubMed PMID: 21813735; PubMed Central PMCID: PMC3183018.

Lord C, Bhandari D, Menon S, Ghassemian M, Nycz D, Hay J, Ghosh P, Ferro-Novick S. Sequential interactions with Sec23 control the direction of vesicle traffic. Nature. 2011 May 12;473(7346):181-6. doi: 10.1038/nature09969. Epub 2011 May 1. PubMed PMID: 21532587; PubMed Central PMCID: PMC3093450.

2010

Barrowman J, Bhandari D, Reinisch K, Ferro-Novick S. TRAPP complexes in membrane traffic: convergence through a common Rab. Nat Rev Mol Cell Biol. 2010 Nov;11(11):759-63. doi: 10.1038/nrm2999. PubMed PMID: 20966969.

Li X, Du Y, Siegel S, Ferro-Novick S, Novick P. Activation of the mitogen-activated protein kinase, Slt2p, at bud tips blocks a late stage of endoplasmic reticulum inheritance in Saccharomyces cerevisiae. Mol Biol Cell. 2010 May 15;21(10):1772-82. doi: 10.1091/mbc.e09-06-0532. Epub 2010 Mar 31. PubMed PMID: 20357006; PubMed Central PMCID: PMC2869382.

Lynch-Day MA, Bhandari D, Menon S, Huang J, Cai H, Bartholomew CR, Brumell JH, Ferro-Novick S, Klionsky DJ. Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7811-6. doi: 10.1073/pnas.1000063107. Epub 2010 Apr 7. PubMed PMID: 20375281; PubMed Central PMCID: PMC2867920.

Sclafani A, Chen S, Rivera-Molina F, Reinisch K, Novick P, Ferro-Novick S. Establishing a role for the GTPase Ypt1p at the late Golgi. Traffic. 2010 Apr;11(4):520-32. doi: 10.1111/j.1600-0854.2010.01031.x. Epub 2010 Jan 6. PubMed PMID: 20059749; PubMed Central PMCID: PMC2861988.

2009

Yamasaki A, Menon S, Yu S, Barrowman J, Meerloo T, Oorschot V, Klumperman J, Satoh A, Ferro-Novick S. mTrs130 is a component of a mammalian TRAPPII complex, a Rab1 GEF that binds to COPI-coated vesicles. Mol Biol Cell. 2009 Oct;20(19):4205-15. doi: 10.1091/mbc.e09-05-0387. Epub 2009 Aug 5. PubMed PMID: 19656848; PubMed Central PMCID: PMC2754934.

Chin HF, Cai Y, Menon S, Ferro-Novick S, Reinisch KM, De La Cruz EM. Kinetic analysis of the guanine nucleotide exchange activity of TRAPP, a multimeric Ypt1p exchange factor. J Mol Biol. 2009 Jun 5;389(2):275-88. doi: 10.1016/j.jmb.2009.03.068. Epub 2009 Apr 8. PubMed PMID: 19361519; PubMed Central PMCID: PMC2770256.

2008

Cai Y, Chin HF, Lazarova D, Menon S, Fu C, Cai H, Sclafani A, Rodgers DW, De La Cruz EM, Ferro-Novick S, Reinisch KM. The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes. Cell. 2008 Jun 27;133(7):1202-13. doi: 10.1016/j.cell.2008.04.049. PubMed PMID: 18585354; PubMed Central PMCID: PMC2465810.

2007

Cai H, Reinisch K, Ferro-Novick S. Coats, tethers, Rabs, and SNAREs work together to mediate the intracellular destination of a transport vesicle. Dev Cell. 2007 May;12(5):671-82. doi: 10.1016/j.devcel.2007.04.005. Review. PubMed PMID: 17488620.

Cai H, Yu S, Menon S, Cai Y, Lazarova D, Fu C, Reinisch K, Hay JC, Ferro-Novick S. TRAPPI tethers COPII vesicles by binding the coat subunit Sec23. Nature. 2007 Feb 22;445(7130):941-4. doi: 10.1038/nature05527. Epub 2007 Feb 7. PubMed PMID: 17287728.

2006

Menon S, Cai H, Lu H, Dong G, Cai Y, Reinisch K, Ferro-Novick S. mBET3 is required for the organization of the TRAPP complexes. Biochem Biophys Res Commun. 2006 Nov 24;350(3):669-77. doi: 10.1016/j.bbrc.2006.09.096. Epub 2006 Sep 28. PubMed PMID: 17027922.

Du Y, Walker L, Novick P, Ferro-Novick S. Ptc1p regulates cortical ER inheritance via Slt2p. EMBO J. 2006 Oct 4;25(19):4413-22. doi: 10.1038/sj.emboj.7601319. Epub 2006 Sep 14. PubMed PMID: 16977319; PubMed Central PMCID: PMC1589985.

Yu S, Satoh A, Pypaert M, Mullen K, Hay JC, Ferro-Novick S. mBet3p is required for homotypic COPII vesicle tethering in mammalian cells. J Cell Biol. 2006 Jul 31;174(3):359-68. doi: 10.1083/jcb.200603044. PubMed PMID: 16880271; PubMed Central PMCID: PMC2064232.

De Craene JO, Coleman J, Estrada de Martin P, Pypaert M, Anderson S, Yates JR 3rd, Ferro-Novick S, Novick P. Rtn1p is involved in structuring the cortical endoplasmic reticulum. Mol Biol Cell. 2006 Jul;17(7):3009-20. doi: 10.1091/mbc.e06-01-0080. Epub 2006 Apr 19. PubMed PMID: 16624861; PubMed Central PMCID: PMC1483037.

2005

Cai H, Zhang Y, Pypaert M, Walker L, Ferro-Novick S. Mutants in trs120 disrupt traffic from the early endosome to the late Golgi. J Cell Biol. 2005 Dec 5;171(5):823-33. doi: 10.1083/jcb.200505145. Epub 2005 Nov 28. PubMed PMID: 16314430; PubMed Central PMCID: PMC2171297.

Estrada de Martin P, Novick P, Ferro-Novick S. The organization, structure, and inheritance of the ER in higher and lower eukaryotes. Biochem Cell Biol. 2005 Dec;83(6):752-61. doi: 10.1139/o05-159. Review. PubMed PMID: 16333327.

Estrada de Martin P, Du Y, Novick P, Ferro-Novick S. Ice2p is important for the distribution and structure of the cortical ER network in Saccharomyces cerevisiae. J Cell Sci. 2005 Jan 1;118(Pt 1):65-77. doi: 10.1242/jcs.01583. Epub 2004 Dec 7. PubMed PMID: 15585575.

2004

Wiederkehr A, De Craene JO, Ferro-Novick S, Novick P. Functional specialization within a vesicle tethering complex: bypass of a subset of exocyst deletion mutants by Sec1p or Sec4p. J Cell Biol. 2004 Dec 6;167(5):875-87. doi: 10.1083/jcb.200408001. PubMed PMID: 15583030; PubMed Central PMCID: PMC2172455.

Du Y, Ferro-Novick S, Novick P. Dynamics and inheritance of the endoplasmic reticulum. J Cell Sci. 2004 Jun 15;117(Pt 14):2871-8. doi: 10.1242/jcs.01286. Review. PubMed PMID: 15197242.

2003

Estrada P, Kim J, Coleman J, Walker L, Dunn B, Takizawa P, Novick P, Ferro-Novick S. Myo4p and She3p are required for cortical ER inheritance in Saccharomyces cerevisiae. J Cell Biol. 2003 Dec 22;163(6):1255-66. doi: 10.1083/jcb.200304030. PubMed PMID: 14691136; PubMed Central PMCID: PMC2173705.

Wiederkehr A, Du Y, Pypaert M, Ferro-Novick S, Novick P. Sec3p is needed for the spatial regulation of secretion and for the inheritance of the cortical endoplasmic reticulum. Mol Biol Cell. 2003 Dec;14(12):4770-82. doi: 10.1091/mbc.e03-04-0229. Epub 2003 Sep 5. PubMed PMID: 12960429; PubMed Central PMCID: PMC284782.

Barrowman J, Wang W, Zhang Y, Ferro-Novick S. The Yip1p.Yif1p complex is required for the fusion competence of endoplasmic reticulum-derived vesicles. J Biol Chem. 2003 May 30;278(22):19878-84. doi: 10.1074/jbc.M302406200. Epub 2003 Mar 25. PubMed PMID: 12657649.

2002

Wang W, Ferro-Novick S. A Ypt32p exchange factor is a putative effector of Ypt1p. Mol Biol Cell. 2002 Sep;13(9):3336-43. doi: 10.1091/mbc.01-12-0577. PubMed PMID: 12221137; PubMed Central PMCID: PMC124163.

2001

Kim DW, Massey T, Sacher M, Pypaert M, Ferro-Novick S. Sgf1p, a new component of the Sec34p/Sec35p complex. Traffic. 2001 Nov;2(11):820-30. doi: 10.1034/j.1600-0854.2001.21111.x. PubMed PMID: 11733049.

Du Y, Pypaert M, Novick P, Ferro-Novick S. Aux1p/Swa2p is required for cortical endoplasmic reticulum inheritance in Saccharomyces cerevisiae. Mol Biol Cell. 2001 Sep;12(9):2614-28. doi: 10.1091/mbc.12.9.2614. PubMed PMID: 11553703; PubMed Central PMCID: PMC59699.

Sacher M, Barrowman J, Wang W, Horecka J, Zhang Y, Pypaert M, Ferro-Novick S. TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport. Mol Cell. 2001 Feb;7(2):433-42. doi: 10.1016/s1097-2765(01)00190-3. PubMed PMID: 11239471.

Sacher M, Ferro-Novick S. Purification of TRAPP from Saccharomyces cerevisiae and identification of its mammalian counterpart. Methods Enzymol. 2001;329:234-41. doi: 10.1016/s0076-6879(01)29083-1. PubMed PMID: 11210539.

2000

Wang W, Sacher M, Ferro-Novick S. TRAPP stimulates guanine nucleotide exchange on Ypt1p. J Cell Biol. 2000 Oct 16;151(2):289-96. doi: 10.1083/jcb.151.2.289. PubMed PMID: 11038176; PubMed Central PMCID: PMC2192651.

Guo W, Sacher M, Barrowman J, Ferro-Novick S, Novick P. Protein complexes in transport vesicle targeting. Trends Cell Biol. 2000 Jun;10(6):251-5. doi: 10.1016/s0962-8924(00)01754-2. Review. PubMed PMID: 10802541.

Barrowman J, Sacher M, Ferro-Novick S. TRAPP stably associates with the Golgi and is required for vesicle docking. EMBO J. 2000 Mar 1;19(5):862-9. doi: 10.1093/emboj/19.5.862. PubMed PMID: 10698928; PubMed Central PMCID: PMC305626.

Sacher M, Barrowman J, Schieltz D, Yates JR 3rd, Ferro-Novick S. Identification and characterization of five new subunits of TRAPP. Eur J Cell Biol. 2000 Feb;79(2):71-80. doi: 10.1078/S0171-9335(04)70009-6. PubMed PMID: 10727015. 

1999

Kim DW, Sacher M, Scarpa A, Quinn AM, Ferro-Novick S. High-copy suppressor analysis reveals a physical interaction between Sec34p and Sec35p, a protein implicated in vesicle docking. Mol Biol Cell. 1999 Oct;10(10):3317-29. doi: 10.1091/mbc.10.10.3317. PubMed PMID: 10512869; PubMed Central PMCID: PMC25597.

1998

Singer-Krüger B, Nemoto Y, Daniell L, Ferro-Novick S, De Camilli P. Synaptojanin family members are implicated in endocytic membrane traffic in yeast. J Cell Sci. 1998 Nov;111 ( Pt 22):3347-56. doi: 10.1242/jcs.111.22.3347. PubMed PMID: 9788876. 

Kaiser C, Ferro-Novick S. Transport from the endoplasmic reticulum to the Golgi. Curr Opin Cell Biol. 1998 Aug;10(4):477-82. doi: 10.1016/s0955-0674(98)80062-8. Review. PubMed PMID: 9719868.

Jiang Y, Scarpa A, Zhang L, Stone S, Feliciano E, Ferro-Novick S. A high copy suppressor screen reveals genetic interactions between BET3 and a new gene. Evidence for a novel complex in ER-to-Golgi transport. Genetics. 1998 Jun;149(2):833-41. doi: 10.1093/genetics/149.2.833. PubMed PMID: 9611195; PubMed Central PMCID: PMC1460158.

Abeliovich H, Grote E, Novick P, Ferro-Novick S. Tlg2p, a yeast syntaxin homolog that resides on the Golgi and endocytic structures. J Biol Chem. 1998 May 8;273(19):11719-27. doi: 10.1074/jbc.273.19.11719. PubMed PMID: 9565594.

Sacher M, Jiang Y, Barrowman J, Scarpa A, Burston J, Zhang L, Schieltz D, Yates JR 3rd, Abeliovich H, Ferro-Novick S. TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion. EMBO J. 1998 May 1;17(9):2494-503. doi: 10.1093/emboj/17.9.2494. PubMed PMID: 9564032; PubMed Central PMCID: PMC1170591.

1997

Singer-Krüger B, Ferro-Novick S. Use of a synthetic lethal screen to identify yeast mutants impaired in endocytosis, vacuolar protein sorting and the organization of the cytoskeleton. Eur J Cell Biol. 1997 Dec;74(4):365-75. PubMed PMID: 9438133.

Sacher M, Stone S, Ferro-Novick S. The synaptobrevin-related domains of Bos1p and Sec22p bind to the syntaxin-like region of Sed5p. J Biol Chem. 1997 Jul 4;272(27):17134-8. doi: 10.1074/jbc.272.27.17134. PubMed PMID: 9202032.

Stone S, Sacher M, Mao Y, Carr C, Lyons P, Quinn AM, Ferro-Novick S. Bet1p activates the v-SNARE Bos1p. Mol Biol Cell. 1997 Jul;8(7):1175-81. doi: 10.1091/mbc.8.7.1175. PubMed PMID: 9243499; PubMed Central PMCID: PMC276144.

1995

Rossi G, Kolstad K, Stone S, Palluault F, Ferro-Novick S. BET3 encodes a novel hydrophilic protein that acts in conjunction with yeast SNAREs. Mol Biol Cell. 1995 Dec;6(12):1769-80. doi: 10.1091/mbc.6.12.1769. PubMed PMID: 8590804; PubMed Central PMCID: PMC301331.

Jiang Y, Proteau P, Poulter D, Ferro-Novick S. BTS1 encodes a geranylgeranyl diphosphate synthase in Saccharomyces cerevisiae. J Biol Chem. 1995 Sep 15;270(37):21793-9. doi: 10.1074/jbc.270.37.21793. PubMed PMID: 7665600.

Simons JF, Ferro-Novick S, Rose MD, Helenius A. BiP/Kar2p serves as a molecular chaperone during carboxypeptidase Y folding in yeast. J Cell Biol. 1995 Jul;130(1):41-9. doi: 10.1083/jcb.130.1.41. PubMed PMID: 7790376; PubMed Central PMCID: PMC2120506.

Jiang Y, Sacher M, Singer-Krüger B, Lian JP, Stone S, Ferro-Novick S. Factors mediating the late stages of ER-to-Golgi transport in yeast. Cold Spring Harb Symp Quant Biol. 1995;60:119-26. doi: 10.1101/sqb.1995.060.01.015. PubMed PMID: 8824384.

Jiang Y, Rossi G, Ferro-Novick S. Characterization of yeast type-II geranylgeranyltransferase. Methods Enzymol. 1995;257:21-9. doi: 10.1016/s0076-6879(95)57006-3. PubMed PMID: 8583924.

1994

Lian JP, Stone S, Jiang Y, Lyons P, Ferro-Novick S. Ypt1p implicated in v-SNARE activation. Nature. 1994 Dec 15;372(6507):698-701. doi: 10.1038/372698a0. PubMed PMID: 7990964.

Ferro-Novick S, Jahn R. Vesicle fusion from yeast to man. Nature. 1994 Jul 21;370(6486):191-3. doi: 10.1038/370191a0. Review. PubMed PMID: 8028665.

Jiang Y, Ferro-Novick S. Identification of yeast component A: reconstitution of the geranylgeranyltransferase that modifies Ypt1p and Sec4p. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4377-81. doi: 10.1073/pnas.91.10.4377. PubMed PMID: 8183917; PubMed Central PMCID: PMC43788.

1993

Jiang Y, Rossi G, Ferro-Novick S. Bet2p and Mad2p are components of a prenyltransferase that adds geranylgeranyl onto Ypt1p and Sec4p. Nature. 1993 Nov 4;366(6450):84-6. doi: 10.1038/366084a0. PubMed PMID: 8232542.

Lian JP, Ferro-Novick S. Bos1p, an integral membrane protein of the endoplasmic reticulum to Golgi transport vesicles, is required for their fusion competence. Cell. 1993 May 21;73(4):735-45. doi: 10.1016/0092-8674(93)90253-m. PubMed PMID: 8500167.

Ferro-Novick S, Novick P. The role of GTP-binding proteins in transport along the exocytic pathway. Annu Rev Cell Biol. 1993;9:575-99. doi: 10.1146/annurev.cb.09.110193.003043. Review. PubMed PMID: 8280472.

1992

Newman AP, Groesch ME, Ferro-Novick S. Bos1p, a membrane protein required for ER to Golgi transport in yeast, co-purifies with the carrier vesicles and with Bet1p and the ER membrane. EMBO J. 1992 Oct;11(10):3609-17. doi: 10.1002/j.1460-2075.1992.tb05445.x. PubMed PMID: 1396561; PubMed Central PMCID: PMC556820.

Newman AP, Graf J, Mancini P, Rossi G, Lian JP, Ferro-Novick S. SEC22 and SLY2 are identical. Mol Cell Biol. 1992 Aug;12(8):3663-4. doi: 10.1128/mcb.12.8.3663-3664.1992. PubMed PMID: 1445580; PubMed Central PMCID: PMC364633.

Groesch ME, Rossi G, Ferro-Novick S. Reconstitution of endoplasmic reticulum to Golgi transport in yeast: in vitro assay to characterize secretory mutants and functional transport vesicles. Methods Enzymol. 1992;219:137-52. doi: 10.1016/0076-6879(92)19016-y. PubMed PMID: 1487987.

1991

Kohl NE, Diehl RE, Schaber MD, Rands E, Soderman DD, He B, Moores SL, Pompliano DL, Ferro-Novick S, Powers S. Structural homology among mammalian and Saccharomyces cerevisiae isoprenyl-protein transferases. J Biol Chem. 1991 Oct 5;266(28):18884-8. PubMed PMID: 1918005.

Ferro-Novick S, Newman AP, Groesch M, Ruohola H, Rossi G, Graf J, Shim J. An analysis of BET1, BET2, and BOS1. Three factors mediating ER to Golgi transport in yeast. Cell Biophys. 1991 Oct-Dec;19(1-3):25-33. doi: 10.1007/bf02989876. Review. PubMed PMID: 1726885.

Rossi G, Yu JA, Newman AP, Ferro-Novick S. Dependence of Ypt1 and Sec4 membrane attachment on Bet2. Nature. 1991 May 9;351(6322):158-61. doi: 10.1038/351158a0. PubMed PMID: 1903184.

Shim J, Newman AP, Ferro-Novick S. The BOS1 gene encodes an essential 27-kD putative membrane protein that is required for vesicular transport from the ER to the Golgi complex in yeast. J Cell Biol. 1991 Apr;113(1):55-64. doi: 10.1083/jcb.113.1.55. PubMed PMID: 2007627; PubMed Central PMCID: PMC2288912.

1990

Newman AP, Ferro-Novick S. Defining components required for transport from the ER to the Golgi complex in yeast. Bioessays. 1990 Oct;12(10):485-91. doi: 10.1002/bies.950121006. Review. PubMed PMID: 2082939.

Groesch ME, Ruohola H, Bacon R, Rossi G, Ferro-Novick S. Isolation of a functional vesicular intermediate that mediates ER to Golgi transport in yeast. J Cell Biol. 1990 Jul;111(1):45-53. doi: 10.1083/jcb.111.1.45. PubMed PMID: 2195039; PubMed Central PMCID: PMC2116157.

Newman AP, Shim J, Ferro-Novick S. BET1, BOS1, and SEC22 are members of a group of interacting yeast genes required for transport from the endoplasmic reticulum to the Golgi complex. Mol Cell Biol. 1990 Jul;10(7):3405-14. doi: 10.1128/mcb.10.7.3405-3414.1990. PubMed PMID: 2192256; PubMed Central PMCID: PMC360773.

1989

Bacon RA, Salminen A, Ruohola H, Novick P, Ferro-Novick S. The GTP-binding protein Ypt1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants. J Cell Biol. 1989 Sep;109(3):1015-22. doi: 10.1083/jcb.109.3.1015. PubMed PMID: 2504726; PubMed Central PMCID: PMC2115776.

Ruohola H, Kabcenell AK, Ferro-Novick S. Reconstitution of transport from the ER to the Golgi complex in yeast using microsomes and permeabilized yeast cells. Methods Cell Biol. 1989;31:143-54. doi: 10.1016/s0091-679x(08)61606-4. PubMed PMID: 2674624.

1988

Ruohola H, Kabcenell AK, Ferro-Novick S. Reconstitution of protein transport from the endoplasmic reticulum to the Golgi complex in yeast: the acceptor Golgi compartment is defective in the sec23 mutant. J Cell Biol. 1988 Oct;107(4):1465-76. doi: 10.1083/jcb.107.4.1465. PubMed PMID: 3049622; PubMed Central PMCID: PMC2115264.

1987

Ruohola H, Ferro-Novick S. Sec53, a protein required for an early step in secretory protein processing and transport in yeast, interacts with the cytoplasmic surface of the endoplasmic reticulum. Proc Natl Acad Sci U S A. 1987 Dec;84(23):8468-72. doi: 10.1073/pnas.84.23.8468. PubMed PMID: 3317409; PubMed Central PMCID: PMC299565.

Newman AP, Ferro-Novick S. Characterization of new mutants in the early part of the yeast secretory pathway isolated by a [3H]mannose suicide selection. J Cell Biol. 1987 Oct;105(4):1587-94. doi: 10.1083/jcb.105.4.1587. PubMed PMID: 3312234; PubMed Central PMCID: PMC2114650.

1986

Beckwith J, Ferro-Novick S. Genetic studies on protein export in bacteria. Curr Top Microbiol Immunol. 1986;125:5-27. doi: 10.1007/978-3-642-71251-7_2. Review. PubMed PMID: 3091324.

1985

Ferro-Novick S. Genetic approaches to the study of protein targeting across a lipid bilayer. Trends in biochemical sciences. 1985 November; 10(11):425-427. doi: 10.1016/0968-0004(85)90023-4.

Ferro-Novick S, Beckwith J. Genetic evidence for the coupling of the synthesis and secretion of proteins in E. coli. In: Protein transport and secretion. Current communications in molecular biology New York, NY: Cold Spring Harbor Laboratory; 1985.

1984

Ferro-Novick S, Honma M, Beckwith J. The product of gene secC is involved in the synthesis of exported proteins in E. coli. Cell. 1984 Aug;38(1):211-7. doi: 10.1016/0092-8674(84)90542-7. PubMed PMID: 6088066.

Ferro-Novick S, Hansen W, Schauer I, Schekman R. Genes required for completion of import of proteins into the endoplasmic reticulum in yeast. J Cell Biol. 1984 Jan;98(1):44-53. doi: 10.1083/jcb.98.1.44. PubMed PMID: 6368572; PubMed Central PMCID: PMC2113014.

Ferro-Novick S, Novick P, Field C, Schekman R. Yeast secretory mutants that block the formation of active cell surface enzymes. J Cell Biol. 1984 Jan;98(1):35-43. doi: 10.1083/jcb.98.1.35. PubMed PMID: 6368571; PubMed Central PMCID: PMC2113008.

1983

Schekman R, Novick P, Ferro-Novick S, Esmon B, Hansen W, Etcheverry T, Stevens T. Protein secretion and organelle assembly in yeast. In: Berkeley Workshop on Recent Advances in Yeast Molecular Biology Berkeley, CA: Berkeley Workshop on Recent Advances in Yeast Molecular Biology; 1983. p.143-155.

Oliver D, Kumamoto C, Brickman E, Ferro-Novick F, Garwin J, Beckwith J. Genetics of the secretory apparatus of E. coli. In: Gene Expression Cetus—UCLA Symposuim Los Angeles, CA: Expression Cetus—UCLA Symposium; 1983. p.371.

Schekman R, Novick P, Ferro-Novick S, Esmon B, Hansen W, Etcheverry T, Stevens T. Protein secretion and organelle assembly in yeast. In: Berkeley Workshop on Recent Advances in Yeast Molecular Biology Berkeley, CA: Berkeley Workshop on Recent Advances in Yeast Molecular Biology; 1983. p.143-155.

1981

Novick P, Ferro S, Schekman R. Order of events in the yeast secretory pathway. Cell. 1981 Aug;25(2):461-9. doi: 10.1016/0092-8674(81)90064-7. PubMed PMID: 7026045.

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