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CBIO Training Program Lecture Schedule

 

2023 / 2024

Date Speaker Lab Title of Talk
06/07/24 Alex Wenzel, Ph.D.
Postdoc Trainee
Mesirov Lab

Machine Learning-Powered NextGen GSEA

05/03/24 Brett Taylor
Predoc Trainee
Furnari/Ren Labs

Extrachromosomal DNA as Driver of Heterogeneity and Plasticity in Glioblastoma

04/05/24 Mike Wang
Predoc Trainee

Hangauer Lab

Cancer Persistent States as Mediators of Acquired Resistance to Immunotherapy

03/01/24 Hugo Medina
Postdoc Trainee

Yeo Lab

RNA Protein Components Mediating Stress Granule Dependency in Acute Myeloid Leukemia

02/02/24 Fanny Zhou
Predoc Trainee

Signer Lab

Proteostasis Loss in Aging Hematopoietic Stem Cells

01/05/24 Mariya Kazachkova
Predoc Trainee

Alexandrov Lab

Understanding differential activity of an ROS mutational signature in colorectal cancers across different countries

12/01/23

(Virtual)

Paul Mischel, M.D., Ph.D. Professor,
Department of Pathology
Stanford University School of Medicine

Extrachromosomal DNA: An Emerging Hallmark in Human Cancer

11/03/23

Bogdan Bintu, Ph.D.

Assistant Professor,
Department of Cellular and Molecular Medicine
UC San Diego School of Medicine

Spatial Transcriptomics, Chromatin Tracing, MERFISH

10/06/23 Jesse Dixon, M.D., Ph.D.

Assistant Professor,
Gene Expression Laboratory
Salk Institute for Biological Studies

The Impact of Structural Variants on 3D Genome Organization in Human Cancers

09/08/23 Mahajani Symposium

https://mahajanisymposium.com/program.html

Advances in Cellular Therapies Against Cancer

2022 / 2023

Date Speaker Lab Title of Talk
06/02/23 Katherine Rothamel, Postdoc Trainee Yeo Lab Exploring RNA-Protein Complexes Required for MYC and KRAS-Driven Breast Cancers
05/05/23 Fanny Zhou, Predoc Trainee Signer Lab The Role of Proteostasis Loss in Aging Hematopoietic Stem Cells on Leukemia Initiation
04/07/23 Mariya Kazachkova, Postdoc Trainee Alexandrov Lab Mapping the Developmental Trajectory of Berrett's Esophagus through Genomic and Microbial Analysis
03/03/23 Mark Kelly, Postdoc Trainee Ideker Lab Defining, Using, adn Dissectign Protein Systems to Understand the Cancer Genome
02/03/23 Shiruyeh Schokrpur, Postdoc Trainee Gutkind Lab Harnessing mRNA Delivery and the XCL1-XCR1 Dendritic Cell Axis to Enhance Cancer Response to Immunotherapy
01/06/23 Juan Hernandez, Predoc Trainee Huang Lab Methyltransferase PRMT5 Promotes Expression of Colon Tumor Stem Cell Marker DCLK1
12/02/22 Bryan Sun, Ph.D. Associate Professor, Department of Dermatology Moscaicism, the Noncoding Genome and the Skin
11/04/22 Shiri Gur-Cohen, Ph.D. Assistant Professor, Department of Medicine Eavesdropping on the Conversation Between Tissue Stem Cells and their Vascular Niches
10/07/22 Sheng Zhong, Ph.D. Professor, Department of Bioengineering Revealing Protein-Protein Interactions at the Transcriptome Scale by Sequencing
09/09/22 Usha Mahajani Symposium on Molecular Medicine Tumor Dormancy

 

2021 / 2022

Date Speaker Lab Title of Talk
06/03/22 Shiruyeh Schokrpur, Postdoc Trainee Gutkind Lab Harnessing mRNA Delivery and the
XCL1-XCR1 Dendritic Cell Axis to
Enhance Cancer Response to Immunotherapy
05/06/22 Mark Kelly, Postdoc Trainee Ideker Lab Mapping Cancer Signaling Pathways
through In Situ Dominant Mutations
04/01/22 Dominic Schenone, Predoc Trainee Heinz Lab HOXB13 Estrogen Receptor (ER)
Re-programming in ER-Positive Breast Cancer
03/04/22 Alex Tankka, Predoc Trainee Yeo Lab Identifying RNA-Binding Protein Vulnerabilities
in Breast Cancers with
Unique Mutational Backgrounds
02/04/22 Stephanie Fraley, Ph.D. Associate Professor,
Department of Bioengineering
Identifying Regulators of
Breast Cancer Heterogeneity through
Phenotypic Sorting and Single Cell Sequencing
01/07/22 Ryan Setten, Postdoc Trainee Yeo Lab Targetting the MLL-AF9 Oncogene
of AML with Antibody-Conjugated
Antisense-Oligonucleotide
12/03/21 Vineet Bafna, Ph.D. Professor, Department of
Computer Science & Engineering
Computational Methods for Analyzing
Extrachromosomal DNA in Cancer
11/05/21 Robert Signer, Ph.D. Assistant Professor, Department of
Medicine, Division of
Rengerative Medicine
Targetting the Proteostasis Network
in Normal and Malignant Stem Cells
10/01/21 Juan Hernandez, Predoc Trainee Huang Lab Methyltransferase PRMT5 Promotes
Expression of Colon Tumor
Stem Cell Marker DCLK1
09/03/21 Pradipta Ghosh,Ph.D. Professor, Cellular and Molecular
Medicine; Director, Institute for
Network Medicine
Grant Writing Workshop
06/04/21 Victoria Wu, Predoc Trainee;
Alexandra Tankka, Predoc Trainee;
Dominic Schenone, Predoc Trainee;
Ryan Setten, Ph.D.,
Postdoc Trainee
Gutkind Lab;
Yeo Lab;
Sven Lab;
Dowdy Lab
GPCRome in Tumor-Targeting T cells;
MicroRNA-mRNA Pairs in MYC-Driven Cancer;
HOXB13 Effects on ER+ Breast Cancer;
Targeting AML Oncogene
05/07/21 External Advisory Committee Meeting with Trainees (55 minutes) with Executive Committee (35 minutes)
04/02/21 Meghana Padagala, Predoc Trainee;
August Williams, Predoc Trainee;
Dan Cunningham-Bryant, Ph.D.,
Postdoc Trainee
Carter Lab;
Hangauer Lab;
Ren Lab
Germine Variant Effects on Immunotherapy;
Apoptotic Nuclease Drives Drug Resistance;
Spatial Epigenomics in Tissues
03/05/21 Ryan Setten, Postdoc Trainee Dowdy Lab Targeted Ablation of AML Oncogene with
Antibody-Conjugated RNAi
03/05/21 Dominic Schenone,
Predoc Trainee
Heinz Lab HOXB13 Estrogen Receptor Reprogramming in
HR+ Breast Cancer
02/05/21 Alexandra Tankka,
Predoc Trainee
Yeo Lab Identification of microRNA-mRNA gene silencing
interactions required for MYC-driven cancer growth
02/05/21 Victoria Wu, Predoc Trainee Gutkind Lab Targeting the Prostaglandin Receptor Gas
Signaling
Axis as a Novel Immune Checkpoint
of Cytotoxic
T-Cells in Cancer
01/08/21 Dan Cunningham-Bryant, Ph.D. Ren Lab Deciphering Context-Specific Enhancer Function
Using Highly Multiplexed Imaging
01/08/21 Esther Park, Ph.D. Rich Lab Targeting Cancer-Specific Innatye Immunity with
Zika Virus
12/04/20 August Williams, Predoc Trainee Hangauer Lab Revealing the Origin of Acquired Drug Resistance
Mutations in Cancer
12/04/20 Meghana Pagadala, Predoc
Trainee
Carter Lab Germline Variants that Modify Tumor-Immune
Interactions
11/06/20 Chris Putnam, Ph.D. Assistant Professor, Department of
Medicine
CRISPR Pickels & Bagel
10/02/20 Jason Sicklick, MD Professor and Executive Vice Chair
of Research, Department of Surgery
Gastrointestinal Stromal Tumor: Slicing the
Genomic
Pie and Cutting Through the Tumor
Microenvironment
09/04/20 Ed Stites, MD, Ph.D. Assitant Professor, Hearst Foundation
Developmental Chair, Salk Institute for
Biological Sciences
Understanding Your Data and How it is Analyzed

 

2020 / 2021

Date Speaker Lab Title of Talk
06/04/21 Victoria Wu, Predoc Trainee;
Alexandra Tankka, Predoc Trainee;
Dominic Schenone, Predoc Trainee;
Ryan Setten, Ph.D.,
Postdoc Trainee
Gutkind Lab;
Yeo Lab;
Sven Lab;
Dowdy Lab
GPCRome in Tumor-Targeting T cells;
MicroRNA-mRNA Pairs in MYC-Driven Cancer;
HOXB13 Effects on ER+ Breast Cancer;
Targeting AML Oncogene
05/07/21 External Advisory Committee Meeting with Trainees (55 minutes) with Executive Committee (35 minutes)
04/02/21 Meghana Padagala, Predoc Trainee;
August Williams, Predoc Trainee;
Dan Cunningham-Bryant, Ph.D.,
Postdoc Trainee
Carter Lab;
Hangauer Lab;
Ren Lab
Germine Variant Effects on Immunotherapy;
Apoptotic Nuclease Drives Drug Resistance;
Spatial Epigenomics in Tissues
03/05/21 Ryan Setten, Postdoc Trainee Dowdy Lab Targeted Ablation of AML Oncogene with
Antibody-Conjugated RNAi
03/05/21 Dominic Schenone,
Predoc Trainee
Heinz Lab HOXB13 Estrogen Receptor Reprogramming in
HR+ Breast Cancer
02/05/21 Alexandra Tankka,
Predoc Trainee
Yeo Lab Identification of microRNA-mRNA gene silencing
interactions required for MYC-driven cancer growth
02/05/21 Victoria Wu, Predoc Trainee Gutkind Lab Targeting the Prostaglandin Receptor Gas
Signaling
Axis as a Novel Immune Checkpoint
of Cytotoxic
T-Cells in Cancer
01/08/21 Dan Cunningham-Bryant, Ph.D. Ren Lab Deciphering Context-Specific Enhancer Function
Using Highly Multiplexed Imaging
01/08/21 Esther Park, Ph.D. Rich Lab Targeting Cancer-Specific Innatye Immunity with
Zika Virus
12/04/20 August Williams, Predoc Trainee Hangauer Lab Revealing the Origin of Acquired Drug Resistance
Mutations in Cancer
12/04/20 Meghana Pagadala, Predoc
Trainee
Carter Lab Germline Variants that Modify Tumor-Immune
Interactions
11/06/20 Chris Putnam, Ph.D. Assistant Professor, Department of
Medicine
CRISPR Pickels & Bagel
10/02/20 Jason Sicklick, MD Professor and Executive Vice Chair
of Research, Department of Surgery
Gastrointestinal Stromal Tumor: Slicing the
Genomic
Pie and Cutting Through the Tumor
Microenvironment
09/04/20 Ed Stites, MD, Ph.D. Assitant Professor, Hearst Foundation
Developmental Chair, Salk Institute for
Biological Sciences
Understanding Your Data and How it is Analyzed

 

2019 / 2020

Date Speaker Lab Title of Talk
06/05/20 Dan Cunningham-Bryant, Ph.D. Ren Lab Engineering Chromatin Loops to Interrogate Role
of Chromatin Structure in Oncogenesis
05/01/20 Dan Lorenz, Ph.D. Yeo Lab Using direct RNA sequencing to uncover RNA
modifications in cancer
04/03/20 Victoria Wu, Predoc Trainee Gutkind Lab Targeting cancer-specific innate immunity with
Zika virus
02/07/20 August Williams, Predoc Trainee Hangauer Lab Revealing the Origin of Acquired Drug Resistance
Mutations in Cancer
01/10/20 Meghana Pagadala,
Predoc Trainee
Carter Lab Germline Variants That Modify Tumor-Immune
Interactions
12/06/19 Erica Silva, Predoc Trainee Ideker Lab A Dynamic Perspective of DNA Damage Response
11/01/19 Ludmil Alexandrov, Ph.D. Assistance Professor, Department of
Cellular and Molecular Medicine
The Repertoire of Mutational Signatures in Human
Cancer
10/04/19 Debashis Sahoo, Ph.D. Assistant Professor, Department of
Pediatrics
Developing Computational Models of Biological
Systems Using Boolean Implication Network
09/06/19 Bing Ren, Ph.D. Professor, Department of Cellular and
Molecular Medicine
Single-Cell Analysis of Genome Regulation

 

2018 / 2019

Date Speaker Lab Title of Talk
06/07/19 Dan Lorenz, Ph.D. Yeo Lab Using direct RNA sequencing to uncover RNA
modifications in cancer
05/03/19 Jason Ear, Ph.D. Ghosh Lab Subcellular localization of Daple regulates distinct
function during CRC progression
04/05/19 Soo Park, MD Bajar Lab DNA methylation patterns in response to
hypomethylating agents in MDS
03/01/19 Ayush Kishore, Ph.D. Gutkind Lab Targeting G protein-coupled receptors in
glioblastoma stem cells
02/01/19 Carlos Medina, Predoc Trainee Dowdy Lab Role of MLL-AF9 fusion oncogene in
establishment, maintenance, and recurrence of
Acute Myeloid
Leukemia
01/04/19 Myan Do, Predoc Trainee Willert Lab WNT/FZD7 signaling in stem cells and cancer
12/07/18 Erica Silva, Predoc Trainee Ideker Lab A dynamic perspective of DNA damage response
11/02/18 Elaine Guo, Predoc Trainee Kolodner Lab Effects of FEN1 loss on cancer cells with BRCA1 or
BRCA2 defects
10/05/18 Gene Yeo, Ph.D. Professor, Department of
Cellular and Molecular
Medicine
RNA binding proteins: Engineers of human health
09/07/18 Chris Putnam, Ph.D. Assistant Professor of Medicine Strategies for understanding results from large
genetic screens

 

2017 / 2018

Date Speaker Lab Title of Talk
06/01/18 Tariq Rana, Ph.D. Professor of Pediatrics TBD
05/04/18 Olivier Harismendy, Ph.D. Asst. Professor of Medicine Evolution and Characterization of Chemo-Resistance at Single-Cell Resolution
04/06/18 S. Park, MD Bejar Lab Genomic Correlates of IL-2 Response in Advanced Melanoma and Renal Cell Carcinoma
03/02/18 Ayush Kishore, Ph.D. Gutkind Lab GNAQ-FAK Signaling in Ocular Melanoma
02/02/18 Nathan Jameson Furnari Lab Epigenetic regulation of EGFR in Glioblastoma
01/05/18 Peter Ly, Ph.D. NIH Pathway to Independence Awardee Rebuilding After Catastrophe: How Cell Division Errors Shape the Cancer Genome
12/01/17 Elaine Guo, BS Kolodner Lab Synthetic Lethal Targeting of BRCA-Deficient Cancer
11/03/17 Jason Ear, Ph.D. Ghosh Lab Dissecting the Role of DAPLE in Colorectal Cancer
10/06/17 Carlos Medina, BS Dowdy Lab Genomics of Recurrent Acute Myeloid Leukemia
09/01/17 Myan Do, BA Willert Lab Wnt Receptor FZD7 in Cancers and ES Cells

 

2016 / 2017

Date Speaker Lab Title of Talk
06/02/17 Jill Mesirov, Ph.D. Medicine Computational Cancer Genomics
05/05/17 Nathan Jameson, Predoc Trainee Furnari Lab Understanding EGFRVIII Genomic Breakpoints through CRISPR Modeling
04/07/17 Wendy Huang, Ph.D. Cellular and Molecular Medicine RNA Helicases and Non-Coding RNA in Immune Regulation
03/03/17 Mohit Jain, MD, Ph.D. Medicine and Pharmacology Cancer Metabolomics
02/03/17 Sven Heinz, Ph.D. Cellular and Molecular Medicine Medical Epigenomics in Chronic Lymphocytic Leukemia
01/06/17 Matteo D'Antonio, Ph.D. Frazer Lab Kataegis Expression Signature in Breast Cancer is Associated with Late Onset, Better Prognosis and Higher HER2 Levels
12/02/16 Jin Zhang, Ph.D. Pharmacology Spatiotemporal Regulation of Signaling
11/04/16 Hannah Carter, Ph.D. Medicine and Bioengineering Network Perturbing Cancer Mutations
10/07/16 Guowei Wu Fu Lab SRPK1 Inhibition in Cancer Signaling
09/09/16 Debashis Sahoo, Ph.D. Pediatrics and Computer Science A New Framework to Understand Cancer Cells

 

2015 / 2016

Date Speaker Lab Title of Talk
05/06/16 Christie Eissler, Ph.D. Zhou Lab The Role of Sumoylation in Chromosome Translocation
04/01/16 Guowei Wu Fu Lab SRPK1: A Tumor Suppressor, Oncogene or Both?
03/04/16 Elaine Guo Kolodner Lab Synthetic Lethality Relationships Involving Genome Instability
02/05/16 Nicholas Kalogriopoulos Ghosh Lab Cross-Talk Between RTKs and Trimeric G Proteins
01/08/16 Nathan Jameson Furnari Lab Chromatin Dynamics and Dysregulation Caused by EGFRvIII Deletion in Glioblastoma
12/04/15 Xiang-Dong Fu, Ph.D. Fu Lab SRPK1: A Potential Key Cancer Target
11/06/15 Peter Ly, Ph.D. Cleveland Lab Fragmentation and Reassembly of a Specific Human Chromosome in Micronuclei
10/02/15 Kelly Frazer, Ph.D. Pediatrics Identification of Driver Mutations in Distal Regulatory Elements in Breast Cancer
09/04/15 Clark Chen, MD/Ph.D. Neurosurgery Epigenetic Regulation of Glioblastoma Tumor Initiation

 

2014 / 2015

Date Speaker Lab Title of Talk
07/10/15 Jun Bao Fan, Ph.D. Zhang Lab ISG15/Protein in Cancer Development: Friend or Foe?
06/05/15 Sebastian Gomez-Cavazos, Ph.D. Oegema Lab Exploring the roles of Plk1 and the Chromosome Passenger Complex during Cytokinesis
05/01/15 Aaron Springer Dowdy Lab Treating Cancer with BioReversible Prodrug RNAi Therapeutics
04/03/15 Cara Bickers Traver Lab Lineage Tracing of Hematopoietic Stem and Progenitors in Zebrafish
03/06/15 Nicholas Kalogriopoulos Ghosh Lab Role of G Proteins in Tumor Glucophagy: Lessons Learned From Diabetes
02/13/15 Christie Eissler, Ph.D. Zhou Lab Investigating the Role of Protein SUMOylation in Cell Cycle Dynamics and Genome Stability
01/09/15 Gen-Sheng Feng, Ph.D. Feng Lab Dissecting the Contradictory Roles of Signaling Molecules in Liver Cancer
12/05/14 Maricel Gozo, Ph.D. Cheresh Lab Stress-Induced Reprogramming of Epithelial Cancers
11/07/14 Pradipta Ghosh, MD/Ph.D. Ghosh Lab

Molecular Engineering to Explore, Access, and Modulate a Cancer Cell's Signaling Code

10/03/14 Paul Mischel, Ph.D. Mischel Lab Targeting EGFR-P13-mTOR Signaling: A Central Role of mTORC2 in Cancer Metabolic Reprogramming
09/05/14 Karen Oegema, Ph.D. Oegema Lab Dynamic Cytoskeletal Rearrangement Underlying Cell Division in Cancer

 

2013 / 2014

Date Speaker Lab Title of Talk
07/11/14 Steve Dowdy, Ph.D. Dowdy Lab Death of a Dogma, Cyclin D Activates Rb by Mono-Phosphorylation
06/06/14 Aaron Springer Dowdy Lab Treating Cancer with BioReversible siRNN Produg RNAi Therapeutics
05/02/14 Julia Nussbacher Yeo Lab Roles of RNA Binding Proteins in RNA Metabolism and Protein Translation
04/04/14 Amelia Richardson Desai Lab Functional Analysis of Cohesin Mutants in Human Cancer
03/07/14 Trey Ideker, Ph.D. Ideker Lab Mapping the Genetic Networks of Cancer
02/07/14 Kun-Liang Guan, Ph.D. Guan Lab The Hippo-YAP Pathway in Organ Size Control and Tumorigenesis
01/10/13 Cara Bickers Traver Lab Building Tools for a Zebrafish Leukemia Model
12/06/13 Frank Furnani, Ph.D. Furnani Lab EGF Receptor in Glioma Biology: Therapeutic Target and a Multifaceted Driver of Pathogenicity
11/01/13 Peter Ly, Ph.D. Cleveland Lab Chromosomal Fragmentation Chromothripsis in Cancer
10/04/13 Maricel Gozo, Ph.D. Cheresh Lab Determining Novel Strategies to Overcome EGFR Resistance
09/06/13 David Traver, Ph.D. Traver Lab Normal and Neoplastic Hematopoiesis
07/05/13 Richard Kolodner, Ph.D. Kolodner Lab DNA Damage Repair Mechanisms Drive Cancer

 

2013 / 2012


Date Speaker Lab Title of Talk
06/07/13 Stephanie Weng Zhang Lab Exploring Mechanisms to Reduce Leukemogenic Potential of AML-1-ETO
05/03/13 Alex Hamil Dowdy Lab siRNN Induced RNAi Responses to Treat Cancer
04/05/13 Gene Yeo, Ph.D. Yeo Lab Studies of RNA Binding Proteins Associated with Neurological Disease
02/01/13 Brian Thacker Esko Lab The Role of Heparan Sulfate 3-O Sulfation in Tumor Angiogenesis
01/04/13 Nicholas Vinckier Sander Lab The Roles of SOX9, HES1, and NGN3 in Progression of Pancreatic Ductal Adnocarcinoma (PDAC)
12/07/12 Julia Nussbacher Yeo Lab RNA Binding Protein Regulation of RNA Metabolism
11/02/12 Pradipta Ghosh, MD/Ph.D. Ghosh Lab Transactivation of G-Protein by Tyrosine Kinases
10/05/12 Kirsten Ludwig, Ph.D. Wang Lab Stem Cell Growth Factor Control of Colon Cancer Invasiveness
09/07/12 Amelia Richardson Desai Lab Cohesin Complexes Mutations in Cancer

 

2011 / 2012

Date Speaker Lab Title of Talk
06/01/12 Nicholas Vinckier Sander Lab Notch Signaling in Progression of Pancreatic Ductal Adenocarcinoma (PDAC)
05/04/12 Alex Hamil Dowdy Lab Induction of Synthetic Lethal RNAi Response to Treat Cancer
04/06/12 Anthony Beas Farquhar Lab Gas Regulation of EEA1 Shuts Down Proliferation Signaling Through GIV (Girdin)
03/02/12 Stephanie Weng Zhang Lab Haploinsufficiency in t(8;21) AML Patients
02/03/12 Brian Thacker Esko Lab Heparan Sulfate 3-O Sulfotransferases in Cancer
01/06/12 Jean Wang, Ph.D. Wang Lab Resistance of Leukemic Stem Cells to Oncogene Targeted Therapies
12/02/11 Spencer Wei Yang Lab Epithelial-Mesenchymal Transition (EMT) Programming During Breast Cancer Metastasis
11/01/11 Brian Meade Dowdy Lab Development of Novel RNAi Therapeutics with New Synthetic Chemistry
10/07/11 Kirsten Ludwig, Ph.D. Wang Lab p190RhoGap and Anillin Modulation of Rho-GTP During Cleavage Furrow Formation
09/09/11 Steve Dowdy, Ph.D. Dowdy Lab Regulation of G1 Cell Cycle Progression in Cancer